Administrative Core

行政核心

• 批准号: 10673113
• 负责人: JENNIFER H ELISSEEFF
• 金额: $ 9.16万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-08-01 至 2026-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10673113
• 关键词: Adoption; Advisory Committees; Aging; Atlases; Benchmarking; Biological; Cataloging; Collaborations; Communication; Computer Analysis; Data; Data Analyses; Data Coordinating Center; Data Management Resources; Data Set; Data Storage and Retrieval; Development; Ensure; Evaluation; Generations; Goals; Image; Immunology; Institution; Leadership; Length; Longevity; Maps; Mus; Procedures; Process; Protocols documentation; Quality Control; Recording of previous events; Reporting; Research Personnel; Site; Specimen; Standardization; Structure; System; Technology; Testing; Tissues; United States National Institutes of Health; Work; analysis pipeline; arm; big data management; computerized data processing; conflict resolution; coping; experience; improved; interest; internal control; meetings; mouse genetics; new technology; operation; programs; response; senescence; sex; single-cell RNA sequencing; tissue mapping

The Administrative Core will provide the governance and coordination structure to spearhead the Atlas generation in the JMN-MSMP. The Administrative Core will coordinate and integrate the Biological Analysis Core (BAC) and Data Analysis Core (DAC), and will ensure harmonization of processes and quality control within the JMN-MSMP and with the SenNet Consortium Organization and Data Coordination Center (CODCC) to provide standardized, high-quality datasets for Atlas generation. The MPIs will engage all key stakeholders in shared governance to ensure that perspectives from all components are considered. This will be achieved through an Executive Committee (EC) consisting of the MPIs, and Core Leaders. The AC will coordinate monthly meetings of the EC to review operations, benchmarks, and metrics for continuous quality improvement; provide a forum to introduce emerging opportunities of interest; and formulate action plans for a coordinated response. Internal and External Advisory Committees will provide regular, expert, arms-length advice on scientific decisions, review progress, and assist with conflict resolution. The Administrative Core will work closely with the NIH program manager and external TMCs and data coordinating centers to communicate processes and datasets. Aim 1. Provide JMN-MSMP interdisciplinary leadership and governance structure. Aim 2. Oversee and Coordinate the Biological Analysis and Data Analysis Cores. Aim 3. Coordinate with other SenNet sites to standardize operations and protocols; and prepare, organize, and maintain JMN-MSMP reports and Atlas development.

行政核心将为矛头提供治理和协调结构 JMN-MSMP中的Atlas Generation。管理核心将协调和集成 生物分析核心（BAC）和数据分析核心（DAC），并将确保协调 JMN-MSP和Sennet财团内的过程和质量控制 组织和数据协调中心（CODCC）提供标准化的高质量 Atlas生成的数据集。 MPI将与所有关键利益相关者共享治理与 确保考虑所有组件的观点。这将通过 由MPI和核心领导人组成的执行委员会（EC）。 AC将协调 欧共体的每月会议，以审查操作，基准和指标的持续质量 改进;提供一个论坛来介绍新兴的感兴趣机会；并配方 采取协调响应的行动计划。内部和外部咨询委员会将提供 关于科学决策，审查进度并协助的常规，专家，长期建议 解决冲突。行政核心将与NIH计划经理紧密合作，并 外部TMC和数据协调中心以通信过程和数据集。 目标1。提供JMN-MSM跨学科领导力和治理结构。 目标2。监督和协调生物分析和数据分析核心。 目标3。与其他Sennet站点协调以标准化操作和协议；和 准备，组织和维护JMN-MSMP报告和地图集开发。