Strategies to Innovate EmeRgENcy Care Clinical trials Network (SIREN) Network - Pittsburgh

创新紧急护理临床试验网络 (SIREN) 网络 - 匹兹堡

• 批准号: 10551627
• 负责人: Clifton W. Callaway
• 金额: $ 39.75万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-07-15 至 2028-01-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10551627
• 关键词: Academic Medical Centers; Acceleration; Accident and Emergency department; Acute; Address; Adoption; Ambulances; Ancillary Study; COVID-19 pandemic; Catheterization; Clinical; Clinical Trials; Clinical Trials Network; Communities; Consent; Coronary; Data; Department of Defense; Development; Distress; Electronic Health Record; Emergency Care; Emergency Medicine; Emergency Situation; Emergency medical service; Emergency research; Emergency treatment; Enrollment; Ensure; Environment; Fellowship; Fostering; Funding; Future; Geography; Health Technology; Home; Hospitals; Informed Consent; Infrastructure; Intensive Care Units; Lead; Leadership; Learning; Life; Location; Mentors; Methods; Nature; Participant; Patient Recruitments; Patients; Phase; Preparation; Procedures; Process; Protocols documentation; Publishing; Research; Research Personnel; Rural; Scientific Advances and Accomplishments; Secure; Site; Structure; Teacher Professional Development; Text Messaging; Time; Training; United States National Institutes of Health; Universities; Work; career; clinical development; community engagement; emergency settings; experience; improved; innovation; mHealth; member; novel; outreach; participant enrollment; recruit; remote consent; screening; skills; success; telepresence; treatment trial

The University of Pittsburgh site for the Strategies to Innovate Emergency Care Clinical Trials Network (SIREN) will continue its leadership as a Hub for recruiting participants into emergency care research. Advancements in acute treatment for time-sensitive and life-threatening conditions requires high quality and rigorous trials. The unexpected nature of emergency conditions sometimes demands that participants enter trials under atypical processes such as an Exception from Informed Consent. Emergency care spans multiple locations including prehospital, emergency department, intensive care unit, and home. An experienced research team will implement pragmatic and successful strategies to accomplish enrollment under all these conditions and in all these settings at multiple sites by addressing the following Aims. 1. Provide administrative structure to rapidly implement and enroll from multiple sites in multiple clinical trials of emergency treatments. 2. Explore strategies to increase recruitment, and consent in emergency treatment trials. 3. Explore strategies to increase quality of emergency care data and to ensure retention of subjects enrolled in emergency settings. 4. Advance participation and training for early career investigators.

匹兹堡大学创新紧急护理临床试验网络战略网站(SIREN)将继续作为招募参与者参与紧急护理研究的中心发挥领导作用。在对时间敏感和危及生命的疾病进行急性治疗方面的进展需要高质量和严格的试验。紧急情况的意外性质有时要求参与者在非典型程序下进行试验，例如知情同意的例外。紧急护理跨越多个地点，包括院前、急诊科、重症监护病房和家庭。一个经验丰富的研究团队将实施务实和成功的战略，通过实现以下目标，在所有这些条件和所有这些环境下在多个地点完成招生。1.提供管理结构，以便快速实施和从多个地点登记参加多个急救临床试验。2.探索在紧急治疗试验中增加招募和同意的策略。3.探讨提高急诊护理数据质量和确保保留在急救环境中登记的受试者的战略。4.促进职业生涯早期调查人员的参与和培训。