Strategies to Innovate EmeRgENcy Care Clinical trials Network (SIREN) - Pittsburgh

项目摘要和摘要 本增刊请求为关键个人提供支持，使匹兹堡大学网站能够 创新急诊临床试验网络(SIREN)继续作为枢纽运营的策略 招募参与者参与急救研究。对中心的不间断支持将确保 成功招募参与者参加以下SEREN试验；ICECAP、BOOST-3和PEDS-ICECAP。 我们将继续支持这些试验的辅助研究：PRECICECAP，Bio-Boost和Electronics-Boost 助推器。我们的具体目标仍然是：1.提供快速实施和注册的管理结构 紧急治疗的临床试验。2.最大限度地减少多中心临床的时间、成本和监管障碍 在紧急情况下的试验。3.探索创新战略，增加识别、招聘和 在紧急治疗试验中同意。4.探索提高急救质量的创新战略 数据，并确保保留在紧急情况下登记的受试者。

Project Summary and Abstract This supplement requests support of effort for key individuals that will allow the University of Pittsburgh site for the Strategies to Innovate Emergency Care Clinical Trials Network (SIREN) to continue operations as a Hub for recruiting participants into emergency care research. Uninterrupted support of the Hub will ensure successful enrollment of participants into the following SIREN trials; ICECAP, BOOST-3, and Peds-ICECAP. We will continue to support the ancillary studies for these trials: PRECICECAP, Bio-BOOST and electro- BOOST. Our specific Aims remain: 1. Provide administrative structure to rapidly implement and enroll in clinical trials of emergency treatments. 2. Minimize time, cost and regulatory barriers to multicenter clinical trials in emergency settings. 3. Explore innovative strategies to increase identification, recruitment, and consent in emergency treatment trials. 4. Explore innovative strategies to increase quality of emergency care data and to ensure retention of subjects enrolled in emergency settings.