Developmental Research Program

项目摘要 威斯康星州前列腺癌孢子发育研究计划（DRP）的大学支持早期- 阶段项目，有潜力开辟新的转化研究领域的机会，并导致 降低前列腺癌患者的发病率和死亡率。发展项目包括研究 专注于基础科学发现，预防，早期发现，治疗，发展预后和 预测性生物标志物以及存活率。DRP提供试点资金，以支持创新和高- 影响前列腺癌的研究，并将征求，建议，审查，选择和监测DRP项目，以确保 DRP资源得到有效利用。 发展研究计划的具体目标是： 1.刺激创建多学科团队，在前列腺癌领域进行有影响力的研究 包括基础、临床和人口研究人员，以及与外部SPORE的合作 机构和调查人员。 2.提供1-2年的资金，以支持可能导致后续赠款的赞助商发起的研究， 临床试验，或对项目可行性的洞察，以及成为未来的SPORE项目。 3.支持高风险、高回报的想法，这些想法对于传统的赠款机制来说可能为时过早，但被认为是 创新和重要的探索。 4.监督受资助的DRP项目的进展情况，并建议哪些项目应提前到全面 SPORE项目。

PROJECT SUMMARY The University of Wisconsin Prostate Cancer SPORE Developmental Research Program (DRP) supports early- phase projects that have the potential to open new areas of translational research opportunity, and lead to reduced morbidity and mortality in patients with prostate cancer. Developmental projects include research focused on basic science discoveries, prevention, early detection, treatment, development of prognostic and predictive biomarkers, as well as survivorship. The DRP provides pilot funding to support innovative and high- impact research in prostate cancer and will solicit, advise, review, select, and monitor DRP projects to ensure that DRP resources are effectively used. The Specific Aims for the Developmental Research Program are to: 1. Stimulate creation of multi-disciplinary teams to conduct impactful research studies in prostate cancer that include basic, clinical, and population researchers, as well as collaboration with outside SPORE institutions and investigators. 2. Provide 1-2 years of funding to support investigator-initiated research that may lead to subsequent grants, clinical trials, or insight on project feasibility, as well as become a future SPORE project. 3. Support high-risk, high-reward ideas that may be too early for traditional grant mechanisms but deemed innovative and important to explore. 4. Monitor progress of funded DRP projects and recommend which projects should be advanced to a full SPORE project.