Administrative Core

行政核心

基本信息

  • 批准号:
    10555682
  • 负责人:
  • 金额:
    $ 123.81万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2023
  • 资助国家:
    美国
  • 起止时间:
    2023-06-01 至 2028-02-29
  • 项目状态:
    未结题

项目摘要

ABSTRACT Administrative Core The mission of the Multicenter Osteoarthritis (MOST) study is to conduct, facilitate, and promote high impact research on the etiology and prevention of osteoarthritis (OA) and its consequences of pain and loss of function. During the proposed 4th cycle of MOST (MOST4), we plan to accomplish this goal through the acquisition, management, analysis and sharing of data on OA, risk factors and functional consequences of disease. The primary goal of the MOST4 Administrative Core is to ensure that processes are in place and functioning to support the accomplishment of this mission. The Administrative Core will manage finances, and the following interactions: 1) internally among the study units (the Cores (Clinical Data Collection and Management, Analysis, Imaging) and Projects); 2) with external researchers; 3) between institutions involved in the MOST study including Boston University; University of Alabama, Birmingham; University of California, San Francisco; University of Iowa; the funding agency (NIA); reading centers; and specialized laboratories.The Administrative Core will be under the leadership of Core co-Leaders Drs. David Felson and Tuhina Neogi, supported by an Executive Committee consisting of the other Cores' leaders. The overall team of MOST4 investigators include a mix of senior experienced NIH-funded faculty and junior faculty establishing their careers with a focus on studies of OA, pain and disability. The first cycle of the MOST study (MOST1) was funded in 2001, and investigators affiliated with this cohort have a long history of collaboration, having published over 180 papers reporting important findings related to OA epidemiology and risk factors, pain, function, and other outcomes. Among the unique features of the study has been the multidisciplinarity of its investigators and research. A range of topics have been studied, including MRI findings in the knee, pain sensitization, biomechanical data such as the ground reaction force, measurement of muscle function, studies of crystal deposition, assessment of physical activity, among others. The current proposal for the 4th cycle of MOST (MOST4) represents an expansion of this multidisciplinary focus. The goals of the Administrative Core are to provide leadership to successfully manage the overall study's execution; plan, direct and integrate all MOST study activities; provide transparent communication across projects and cores; and foster cross-project collaboration. We will accomplish these goals through providing leadership and administrative oversight for the following Specific Aims: Scientific & Operational Management, including single Institutional Review Board processes; Financial Management; Study Output Management & Dissemination; Pilot Grant Program; Community Advisory Board Engagement; Communications & External Collaboration. Through these activities, the Administrative Core will ensure the successful operations of MOST4 under the strong and collaborative leadership of the investigator team.
行政核心

项目成果

期刊论文数量(0)
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会议论文数量(0)
专利数量(0)

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DAVID Tobin FELSON其他文献

DAVID Tobin FELSON的其他文献

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{{ truncateString('DAVID Tobin FELSON', 18)}}的其他基金

Project 2: Synovial Fluid Proteomics
项目2:滑液蛋白质组学
  • 批准号:
    10555687
  • 财政年份:
    2023
  • 资助金额:
    $ 123.81万
  • 项目类别:
Novel Insights into Osteoarthritis, Pain and Function: MOST4
对骨关节炎、疼痛和功能的新见解:MOST4
  • 批准号:
    10555681
  • 财政年份:
    2023
  • 资助金额:
    $ 123.81万
  • 项目类别:
Administrative Core
行政核心
  • 批准号:
    10669160
  • 财政年份:
    2019
  • 资助金额:
    $ 123.81万
  • 项目类别:
Boston University CCCR
波士顿大学CCCR
  • 批准号:
    10017004
  • 财政年份:
    2019
  • 资助金额:
    $ 123.81万
  • 项目类别:
Boston University CCCR
波士顿大学CCCR
  • 批准号:
    10466814
  • 财政年份:
    2019
  • 资助金额:
    $ 123.81万
  • 项目类别:
Boston University CCCR
波士顿大学CCCR
  • 批准号:
    10669159
  • 财政年份:
    2019
  • 资助金额:
    $ 123.81万
  • 项目类别:
Administrative Core
行政核心
  • 批准号:
    10466815
  • 财政年份:
    2019
  • 资助金额:
    $ 123.81万
  • 项目类别:
Administrative Core
行政核心
  • 批准号:
    10017050
  • 财政年份:
    2019
  • 资助金额:
    $ 123.81万
  • 项目类别:
Fats, Fiber and Osteoarthritis
脂肪、纤维和骨关节炎
  • 批准号:
    9364179
  • 财政年份:
    2017
  • 资助金额:
    $ 123.81万
  • 项目类别:
Institutional Career Development
机构职业发展
  • 批准号:
    10086525
  • 财政年份:
    2015
  • 资助金额:
    $ 123.81万
  • 项目类别:

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