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中文摘要
翻译
在过去的二十年里,缅因州医疗中心研究所,缅因州健康的一个组成部分,已经建立了一个 高度竞争的研究计划,包括基础,转化,临床和卫生服务研究 支持和提高缅因州的医疗保健需求。我们专注于发展基础生物医学 支持翻译计划的研究得到了生物医学中心的支持。 卓越研究(2000年至今),2017年,多机构北方新英格兰临床和 转化研究网络,以建立扩大临床研究工作所需的基础设施。我们 一直专注于医疗培训项目,与塔夫茨大学有着突出的学术联系 大学医学院,40名医学生参加了缅因州的跟踪项目,20名正在进行中 住院医师和奖学金计划。值得注意的是,最近在研究生医学教育的扩展包括 在我们的内科住院医师中增加了农村轨道,并加强了对研究的关注,作为 居住和奖学金。这些努力得到了机构投资的支持, 学生和医生在扩大研究的选择,以及研究导师与这些对齐 嵄 彸诺丅缅因州医学中心的研究和临床优势包括与以下方面高度相关的主题: NHLBI的使命,包括血管壁生物学、血管发育、心肌损伤、心力衰竭, 血管祖细胞、血管炎症、脂肪/血管相互作用、内皮功能障碍和 心血管疾病;以及针对心脏骤停、囊性纤维化、出血性休克 创伤的血管并发症和疾病的遗传学/流行病学。该提案要求所需的 支持实现NHLBI的目标,发展生物医学研究队伍,重点是独特的 缅因州的医学生人口。该提案要求资金集中于提供严格的、全职的 为缅因州田径医学生提供暑期研究培训体验。虽然有些学生可能 我已经对研究感兴趣,这个新项目将扩大我们的教育范围,包括 转化生物医学研究目前,所有缅因州轨道的学生都需要完成一个学术 项目作为他们医学培训的一部分,我们有一个既定的基础设施,以支持研究 在第一年学习后的夏天。我们的愿景是加强这一渠道, 一群经过严格培训的医生,他们在基础-转化-临床 研究频谱,以促进公众健康。虽然这是一个长期和雄心勃勃的目标,但它更 在缅因州这样的农村州,没有一个大型学术投资组合的环境中, 医学中心,吸引了大量的医学生,居民或研究员感兴趣的翻译 research.该提案要求为医学院学生提供10个短期暑期经验的资金, 塔夫茨缅因州轨道与经验丰富的导师致力于促进导师和培训。
英文摘要
Over the past two decades, Maine Medical Center Research Institute, a component of MaineHealth, has built a highly competitive research program encompassing basic, translational, clinical, and health services research to support and enhance the healthcare needs of the state of Maine. Our focus on developing basic biomedical research to support translational programs has been supported by the formation of Centers of Biomedical Research Excellence (2000-present), and in 2017, a multi-institute Northern New England Clinical and Translational Research Network to establish infrastructure required for extending clinical research efforts. We have maintained a focus on medical training programs, with prominent academic affiliations with Tufts University School of Medicine, with 40 of their medical students in a Maine Track program and 20 ongoing residency and fellowship programs. Of note, recent expansions in graduate medical education include the addition of a Rural Track in our Internal Medicine residency, and an enhanced focus on research as part of residency and fellowships. These efforts have been bolstered by institutional investments to support medical students and physicians in expanded options for research, and the alignment of research mentors with these commitments. Research and clinical strengths at Maine Medical Center include topics of high relevance to the mission of the NHLBI, including vessel wall biology, vascular development, myocardial injury, heart failure, vascular progenitor cells, vascular inflammation, adipose/vascular interactions, endothelial dysfunction and cardiovascular disease; and clinical research addressing cardiac arrest, cystic fibrosis, hemorrhagic shock, vascular complications of trauma, and genetics/epidemiology of disease. This proposal requests the needed support to fulfill the objective of the NHLBI to develop the biomedical research workforce focusing on a unique population of medical students in Maine. This proposal requests funds to focus on providing rigorous, full-time summer research training experiences for Maine Track medical students. While some of those students may already have an interest in research, this new program will broaden our educational scope to include translational biomedical research. Currently, all Maine Track students are required to complete a scholarly project as part of their medical training, and we have an established infrastructure to support research experiences in the summer after the first year of study. Our vision is to enhance this pipeline to increase our community of rigorously trained physicians who are comfortable working across the basic-translational-clinical research spectrum to promote public health. While this is a long-term and ambitious goal, it is even more pressing in an environment such as the rural state of Maine, which does not have a portfolio of large academic medical centers that attract a high number of medical students, residents or fellows interested in translational research. This proposal requests funding for ten short-term summer experiences for medical students in the Tufts Maine Track with experienced mentors committed to promotion of mentorship and training.
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Regulation of arterial phenotype by perivascular adipose tissue in cardiometabolic disease
  • 批准号:
    9495408
  • 项目类别:
  • 资助金额:
    $50.62万
  • 财政年份:
    2018
  • 负责人:
    Lucy Liaw
  • 依托单位:
Regulation of arterial phenotype by perivascular adipose tissue in cardiometabolic disease
  • 批准号:
    9977874
  • 项目类别:
  • 资助金额:
    $50.93万
  • 财政年份:
    2018
  • 负责人:
    Lucy Liaw
  • 依托单位:
Regulation of arterial phenotype by perivascular adipose tissue in cardiometabolic disease
  • 批准号:
    10443027
  • 项目类别:
  • 资助金额:
    $57.02万
  • 财政年份:
    2018
  • 负责人:
    Lucy Liaw
  • 依托单位:
Regulation of arterial phenotype by perivascular adipose tissue in cardiometabolic disease
  • 批准号:
    10231190
  • 项目类别:
  • 资助金额:
    $50.93万
  • 财政年份:
    2018
  • 负责人:
    Lucy Liaw
  • 依托单位:
海外基金