Development Core

项目摘要/摘要(开发核心) 结束结核病流行需要多方面的方法，包括基础科学发现、数据科学、 流行病学、临床试验和实施。发现和应用解决方案、训练有素的熟练结核病 需要专家创建有效实施的数据驱动战略。的主要目标是 发展的核心是招募、培训和支持一支充满活力的结核病科学家队伍，他们将提供高影响力 为结束这一流行病作出重大贡献的领导力。开发核心将专注于新的 研究人员(NIS)在他们的职业生涯之初，以及更多对结核病研究新手的老牌科学家。 核心预算资源调拨目标发展核心将与SEA-核心预算资源调拨目标的其他核心密切合作，通过 以威斯康星州结核病研究和培训中心(TRTC)的初步努力和成功为基础。具体地说，这 将包括扩展现有计划和新设计的计划，以促进下一步的发展 一代科学家，他们将成为结束结核病流行的世界领导者。 在目标1中，我们通过招募结核病研究和发展领导者的新受训人员，专注于早期结核病培训渠道 谁将影响结核病流行启动新的结核病本科计划(TBUP)，扩大我们最近的 制定结核病学者计划(TBSP)，支持本科生研究和培训学员 属于历史上代表性不足的少数群体，并制定新的结核病领导计划(TBLP) 为新的研究人员(研究生和博士后)培养他们向独立的过渡。在目标2中，我们 开发和整合课程机会与临床和转化学、基础科学和 数据科学核心，包括研讨会(包括手稿写作和模拟NIH拨款审查)、课程和 每月研讨会系列，将提供高质量的结核病内容，并纳入威斯康星州大学电子学习计划和 远程学习，以增加广大学习者的可及性。在目标3中，我们将资助催化 发展项目奖，通过初步数据产生动力，支持新的方向 在较大的独立资助拨款申请中使用。这将包括专注于新业务的机会 通过新研究人员奖(NIA)的调查人员(NI)和更多进入结核病的老牌调查人员 通过结核病新人奖(N2TB)进行研究。我们还将为获奖者提供资金，以传播他们的 通过Awardee Support Grants(ASG)出版或在科学会议上发表成果。一起， 这些努力将促进下一代科学家的发展，他们将成为世界上在 结核病的流行。

PROJECT SUMMARY/ABSTRACT (DEVELOPMENT CORE) Ending the TB epidemic requires a multifaceted approach which spans basic science discovery, data science, epidemiology, clinical trials, and implementation. To discover and apply solutions, highly trained and skilled TB experts are required to create data-driven strategies that are effectively implemented. The primary goal of the Development Core is to recruit, train, and support a vibrant cadre of TB scientists who will provide high impact leadership with major contributions to ending the epidemic. The Development Core will focus on new investigators (NIs) at the start of their careers and more established scientists who are new to TB research. The TRAC Developmental Core will work closely with other SEA-TRAC Cores to address knowledge gaps by building on the initial efforts and success of the UW TB Research and Training Center (TRTC). Specifically, this will include expansion of existing programs and newly designed initiatives to foster the development of the next generation of scientists who will be world leaders in ending the TB epidemic. In Aim 1, we focus on the early TB training pipeline by recruiting new trainees in TB research and develop leaders who will impact the TB epidemic launching a new TB Undergraduate Program (TBUP), expand our recently developed TB Scholars Program (TBSP), which supports undergraduate research and training for trainees belonging to historically underrepresented minority groups and develop a new TB Leadership Program (TBLP) for new investigators (graduate and post-doctoral level) to foster their transition to independence. In Aim 2, we develop and integrate curricular opportunities with the Clinical and Translational Science, Basic Science, and Data Science Cores with workshops (including manuscript writing and mock NIH grant review), courses, and monthly seminar series, that will provide high quality TB content and incorporate UW E-learning initiative and remote learning to increase accessibility to a broad cadre of learners. In Aim 3, we will fund catalytic developmental project awards to generate momentum through preliminary data and support new directions for use in larger independently funded grant submissions. This will include opportunities focused on new investigators (NI) through New Investigator Awards (NIAs) and more established investigators entering TB research through New to TB awards (N2TBs). We will also provide funding for awardees to disseminate their results through publication or presentation at scientific meetings via Awardee Support Grants (ASG). Together, these efforts will foster the development of the next generation of scientists who will be world leaders in ending the TB epidemic.