Administrative Core

摘要 管理核心(核心C)的主要目标是支持和促进计划和数据 该TBRU的管理目标。在其职责中，Core C将提供领导力，以确保 在决策中对所有核心和附属研究人员进行强有力的监督和代表，促进整合 研究项目，并与其他结核病研究单位和更广泛的传染病社区建立联系。 我们将成立一个由联合调查员组成的内部项目领导小组(PLT)，他们将定期 评估项目和核心项目的进展情况。我们将在出现需求时确定它们，并审查和 可能会修改优先事项和研究方向。我们将在计划中以两个目标来实施这些努力 管理和数据管理。计划管理计划包括行政结构和 治理、沟通、财务管理、法规遵从性和评估。核心C数据 管理计划将指导所有研究地点的数据管理。核心C的一项重要活动将是 促进位于世界各地的TBRU成员之间的沟通以及与 并将组织和管理一些定期安排的会议，其中一些专门针对 PLT的成员和整个研究团队的其他成员。这些各种会议将提供重要的 有机会分享和讨论总体研究方向和具体的实验问题。《核心》 将计划每年一次的研讨会，届时将有TBRU全体教职员工的演讲以及来自 传染病界的其他成员。核心C将领导TBRU中心的维护 网站和共享文件服务器。为了提供正式的现场审查和与NIH的参与，核心将组织 一年一度的外部科学咨询小组会议，在会议上，MPI和关键人员将与NIH会面 计划工作人员审查活动。总体而言，行政核心将确保项目富有成效， 协同作用，并有足够的支持和资源蓬勃发展。

Abstract The primary goal of the Administrative Core (Core C) is to support and promote the program and data management goals of this TBRU. Amongst its responsibilities, Core C will provide leadership that ensures strong oversight and representation of all the Core and Affiliate Researchers in decisions, facilitate integration of research projects, and connect with other TB Research Units and the broader infectious disease community. We will form an internal Program Leadership Team (PLT) consisting of the Co-Investigators, who will regularly evaluate progress of the Projects and Cores. We will identify needs as they arise, as well as review and possibly modify priorities and research directions. We will implement these efforts with two Aims in Program Management and Data Management. The Program Management plan includes administrative structure and governance, communication, financial management, regulatory compliance, and evaluation. The Core C Data Management Plan will guide management of data across all study sites. A vital activity of Core C will be to facilitate communication amongst the TBRU members located around the world and with the other members of the community and will organize and manage a number of regularly scheduled meetings, some specifically for members of the PLT and others for the entire research team. These various meetings will provide important opportunities to share and discuss overall research directions and specific experimental concerns. The Core will plan yearly workshops which will feature talks by all TBRU faculty members as well as presentations from other members of the infectious disease community. Core C will lead the maintenance of the TBRU Center website and shared file servers. To provide formal site review and involvement with NIH, the Core will organize an annual External Scientific Advisory Group Meeting, in which the MPIs and key personnel will meet with NIH program staff to review activities. Overall, the Administrative Core will ensure that projects are productive, synergistic and have sufficient support and resources to flourish.