Extrastriate Mechanisms of Visuospatial Perception During Eye Movements
眼动过程中视觉空间感知的外在机制
基本信息
- 批准号:10595543
- 负责人:
- 金额:$ 38.13万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2020
- 资助国家:美国
- 起止时间:2020-06-01 至 2025-03-31
- 项目状态:未结题
- 来源:
- 关键词:AreaAttention deficit hyperactivity disorderBehavioralBrainComputer ModelsComputing MethodologiesDataDiseaseDyskinetic syndromeDyslexiaElectrophysiology (science)ExhibitsExperimental ModelsEyeEye MovementsGenerationsHourHumanImpairmentLinkLocationMeasuresMemoryMental disordersMethodsModelingMonkeysMotionNatureNeuronsParkinson DiseasePerceptionPhysiologicalPositioning AttributePrefrontal CortexProcessPsychophysicsReadingRetinaRoleSaccadesSchizophreniaSensorySeriesSignal InductionSourceStatistical ModelsStimulusSystemTechniquesTemporal LobeTestingTimeVisionVisualVisual MotionVisual PerceptionVisual SystemVisuospatialautism spectrum disorderdata-driven modelextrastriateextrastriate visual cortexfrontal eye fieldsinsightneuralneural circuitneural patterningneuromechanismneurophysiologynonhuman primatenoveloculomotorpharmacologicreceptive fieldresponseretinal imagingscreeningvisual informationvisual processingvisual stimulus
项目摘要
PROJECT SUMMARY
We move our eyes thousands of times each day, adding up to over an hour of our waking perception. These
eye movements create considerable difficulties for the brain’s visual processing system, which must suppress
the induced motion of the visual scene caused by the eye movement and provide a stable visual perception
despite these discontinuities. How the visual system deals with the potentially disruptive consequences of our
frequent eye movements is a question with direct relevance for our everyday visual perception, and especially
to disorders in which eye movements are abnormal or the integration of information is impaired, such as
schizophrenia, attention deficit hyperactivity disorder, and autism spectrum disorders; the integration of
information across eye movements may be particularly important in reading, and potentially impaired in mental
disorders such as dyslexia. Aim 1 of this proposal develops a novel statistical approach capable of producing
an encoding model which captures the fast changes in neural sensitivity around the time of eye movements,
and linking this activity to a perceptual readout. This approach reveals a novel neurophysiological
phenomenon—persistent activity in response to stimuli appearing near the time of the saccade—which
contributes to integrating the visual scene across saccades. In Aim 2, we apply the same modelling framework
to the phenomenon of perceived changes in the location of visual stimuli around the time of saccades, and
measure this phenomenon behaviorally in nonhuman primates. The impact of Frontal Eye Field (FEF) activity
on the modulation of extrastriate neuronal responses during eye movements is causally tested using
pharmacological manipulation in Aim 3. The combination of psychophysical, electrophysiological,
computational, and causal manipulation techniques used in this proposal promises an unprecedented level of
insight into how our brain actively reconstructs the visual world three times a second to provide us with a stable
sense of the visual world during eye movements.
项目总结
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
数据更新时间:{{ journalArticles.updateTime }}
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
Neda Nategh其他文献
Neda Nategh的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('Neda Nategh', 18)}}的其他基金
Extrastriate Mechanisms of Visuospatial Perception During Eye Movements
眼动过程中视觉空间感知的外在机制
- 批准号:
10159932 - 财政年份:2020
- 资助金额:
$ 38.13万 - 项目类别:
Extrastriate Mechanisms of Visuospatial Perception During Eye Movements
眼动过程中视觉空间感知的外在机制
- 批准号:
10376258 - 财政年份:2020
- 资助金额:
$ 38.13万 - 项目类别:
相似海外基金
Understanding the relationship between cannabis use and attention-deficit/hyperactivity disorder
了解大麻使用与注意力缺陷/多动症之间的关系
- 批准号:
2874883 - 财政年份:2023
- 资助金额:
$ 38.13万 - 项目类别:
Studentship
RestEaze: A Novel Wearable Device and Mobile Application to Improve the Diagnosis and Management of Restless Legs Syndrome in Pediatric Patients with Attention Deficit/Hyperactivity Disorder
RestEaze:一种新型可穿戴设备和移动应用程序,可改善注意力缺陷/多动症儿科患者不宁腿综合症的诊断和管理
- 批准号:
10760442 - 财政年份:2023
- 资助金额:
$ 38.13万 - 项目类别:
Diagnosis and Treatment of Adult Attention-Deficit/Hyperactivity Disorder: A Workshop
成人注意力缺陷/多动症的诊断和治疗:研讨会
- 批准号:
10825708 - 财政年份:2023
- 资助金额:
$ 38.13万 - 项目类别:
Maternal Attention Deficit Hyperactivity Disorder (m-ADHD): Mental Health, Pregnancy and Infant Outcomes
母亲注意力缺陷多动障碍 (m-ADHD):心理健康、妊娠和婴儿结局
- 批准号:
488888 - 财政年份:2023
- 资助金额:
$ 38.13万 - 项目类别:
Operating Grants
SBIR Phase I: A novel caregiver-centered mobile app and artificial intelligence (AI) coaching intervention for pediatric Attention Deficit Hyperactivity Disorder (ADHD)
SBIR 第一阶段:一款新颖的以护理人员为中心的移动应用程序和人工智能 (AI) 辅导干预儿童注意力缺陷多动障碍 (ADHD)
- 批准号:
2335539 - 财政年份:2023
- 资助金额:
$ 38.13万 - 项目类别:
Standard Grant
Machine Learning Methods to Develop and Deploy Real-Time Risk Surveillance for Autism Spectrum Disorder and Attention Deficit Hyperactivity Disorder from the Electronic Health Record
用于开发和部署电子健康记录中自闭症谱系障碍和注意力缺陷多动障碍实时风险监测的机器学习方法
- 批准号:
10449468 - 财政年份:2022
- 资助金额:
$ 38.13万 - 项目类别:
Do Cerebrovascular Factors mediate the possible link between later-life Attention-Deficit/Hyperactivity Disorder and the development of Lewy Body Diseases?
脑血管因素是否介导晚年注意力缺陷/多动障碍与路易体疾病发展之间的可能联系?
- 批准号:
460431 - 财政年份:2022
- 资助金额:
$ 38.13万 - 项目类别:
Defining Embodied Characteristics of Decision Making in Attention Deficit Hyperactivity Disorder
定义注意力缺陷多动障碍决策的具体特征
- 批准号:
10316100 - 财政年份:2022
- 资助金额:
$ 38.13万 - 项目类别:
The biological connection between educational attainment and attention-deficit/hyperactivity disorder in contrasting environments
对比环境中教育程度与注意力缺陷/多动症之间的生物学联系
- 批准号:
10677008 - 财政年份:2022
- 资助金额:
$ 38.13万 - 项目类别:
Conceptualising and Measuring Attention-Deficit Hyperactivity Disorder (ADHD) Across the Lifespan
在整个生命周期中概念化和测量注意力缺陷多动障碍 (ADHD)
- 批准号:
2689864 - 财政年份:2022
- 资助金额:
$ 38.13万 - 项目类别:
Studentship