Ring-Strain Relief: Applications in Total Synthesis

环应力消除：全合成中的应用

• 批准号: DP200100722
• 负责人: Prof Mark Rizzacasa
• 金额: $ 9.48万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2020
• 资助国家: 澳大利亚
• 起止时间: 2020-01-01 至 2022-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP200100722
• 关键词: Ring; Strain; Relief; Applications; Total

This proposal aims to investigate the chemical synthesis of a number of structurally different natural product target molecules by strategies involving the use of either three or four membered ring-strained compounds to afford key synthetic intermediates in an efficient manner. The key aim of this research is to provide more efficient routes to complex natural products and analogues. The research strives to be at the forefront of modern synthetic organic chemistry and aims to contribute to the Science of complex molecule synthesis.

该提案旨在研究通过涉及使用三元或四元环应变化合物的策略来化学合成许多结构不同的天然产物靶分子，以有效的方式提供关键的合成中间体。这项研究的主要目的是提供更有效的路线复杂的天然产物和类似物。该研究致力于处于现代合成有机化学的最前沿，旨在为复杂分子合成科学做出贡献。