Lessons From Nature: Late Stage Oxidation in Total Synthesis

点击翻译按钮获取中文摘要

This project aims to achieve the chemical synthesis of a number of biologically active novel natural products. The key aspect is the application of chemistry inspired by Nature to deliver molecular complexity in a rapid fashion which would allow for the production of molecules otherwise unavailable in sufficient quantities from the natural sources. This research will utilize late stage oxidation of intermediates to provide ready access to complex molecules. The main goal is the development of new chemical and biological catalysts for further application in organic synthesis with a view to the production of new medicinal agents and important materials.