ACYCLOVIR VS VIDARABINE IN NEONATAL HERPES SIMPLEX INFECTION

阿昔洛韦与阿糖腺苷在新生儿单纯疱疹感染中的比较

• 批准号: 3783480
• 负责人: ROBERT F PASS
• 金额: --
• 依托单位: UNIVERSITY OF ALABAMA AT BIRMINGHAM
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3783480
• 关键词: Herpes simplex disease; acyclovir; dosage; herpes simplex virus 1; human subject; human therapy evaluation; infectious encephalitis; microorganism disease chemotherapy; newborn human (0-6 weeks)

This collaborative study will evaluate high dose acyclovir vs vidarabine for neonatal herpes simplex virus infection in babies with encephalitis (CNS) or disseminated disease. It is designed to assess morbidity and mortality, evaluate dosing regimens and assess persistent viral excretion at peripheral sites.

这项合作研究将评估高剂量阿昔洛韦与阿糖腺苷 用于新生儿单纯疱疹病毒感染脑炎婴儿 （中枢神经系统）或播散性疾病。 它旨在评估发病率和 死亡率，评估给药方案并评估持续病毒排泄 在外围站点。