Jackson Heart Study (JHS) Graduate Training and Education Center (GTEC) - Sheila Malone Diversity Supplement

杰克逊心脏研究 (JHS) 研究生培训和教育中心 (GTEC) - Sheila Malone 多样性补充资料

• 批准号: 10499086
• 负责人: MARINELLE PAYTON
• 金额: $ 4.04万
• 依托单位: JACKSON STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-30 至 2023-09-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10499086
• 关键词: African American; Age; Ancillary Study; Area; Blood Pressure; Blood coagulation; Body Size; Cardiovascular Diseases; Cholesterol; Clinic; Clinical; Communities; Community Health Education; Coronary artery; County; Data; Data Analyses; Diabetes Mellitus; Discrimination; Disease; Electrocardiogram; Event; Family member; Future; Genetic; Glucose; Habits; Health Promotion; Height; Hospitalization; Hypertension; Institutes; Institution; Interview; Investigation; Jackson Heart Study; Knowledge; Laboratories; Life Style; Lipids; Manuscripts; Mathematics; Measurement; Medical History; Medical center; Mentorship; Minority; Mississippi; National Heart, Lung, and Blood Institute; Neck; Obesity; Outpatients; Participant; Pharmaceutical Preparations; Phase; Physical assessment; Physiological; Population; Prevalence; Prevention; Publications; Questionnaires; Research; Research Personnel; Resources; Risk Factors; Science; Series; Site; Socioeconomic Status; Students; Testing; Time; Training; Training and Education; Ultrasonography; United States National Institutes of Health; Universities; Validation; Visit; Weight; Woman; base; career; cohort; college; epidemiology study; falls; graduate student; health disparity; improved; innovation; interest; men; metropolitan; minority health; programs; prospective; pulmonary function; recruit; risk prediction; social; social culture; undergraduate student

The Jackson Heart Study (JHS), the largest investigation of CVD undertaken in an African-American population, is a single-site prospective epidemiologic investigation in the Jackson, Mississippi metropolitan area of Hinds, Madison, and Rankin counties. The JHS is sponsored by the National Heart, Lung, and Blood Institute (NHLBI) and the National Institute of Minority Health and Health Disparities (NIMHD) at the National Institutes of Health (NIH). The JHS started as a partnership between three local institutions: Jackson State University, Tougaloo College, and the University of Mississippi Medical Center and recruited 5,306 African-American men and women between the ages of 35 and 84. Family members were included in order to permit studies of familial and genetic contributions to CVD. The initial examination phase of the study lasted from the fall of 2000 to March 2004 and involved an extensive examination that included a series of questionnaires (dealing with lifestyle habits, medical history, medications, social and cultural factors), physical assessments (height, weight, body size, blood pressure, electrocardiogram, ultrasound measurements of the heart and arteries in the neck, and lung function) and laboratory measurements (cholesterol and other lipids, glucose, indicators related to clotting of the blood, among others). The information collected in this study includes both conventional risk factors and new or emerging factors that may be related to CVD. It also included newer areas of focus comprising early indicators of disease, genetics, socio-cultural influences, such as socioeconomic status and discrimination, and physiological relations between common disorders such as high blood pressure, obesity and diabetes and their influence on CVD. Exam 2 was conducted between 2005 and 2008, and Exam 3 from 2009 to 2012. The next phase of the JHS extended from 2013-2018 and did not include a clinic exam. The five major aims of the JHS are: (1) Support dedicated time for JHS investigators to conduct data analysis and prepare manuscripts using the wealth of collected JHS data; (2) Facilitate access to study resources and expertise in order to: (a) engage researchers beyond the JHS in collaborative analysis of existing data to produce high quality publications; (b) serve as a training ground for undergraduate and graduate students and early career investigators, as appropriate, to help ameliorate the shortage of minority biomedical researchers; and (c) serve as a platform for ancillary studies; (3) Conduct annual interviews with participants to identify interim hospitalizations and outpatient visits, convey information about the JHS, and serve as a vehicle to recruit for ancillary studies; (4) Continue clinical events identification, investigation, and validation to improve statistical power for risk prediction and hypothesis testing; (5) Perform community health education activities to disseminate health promotion and prevention messages in the Jackson community. The JHS Graduate Training and Education Center (GTEC) has four objectives that will serve to help the JHS achieve all of its aims in general and, in particular, Aim 2b listed above. The four objectives of the GTEC are to: (1) strengthen the base of participating students' knowledge of science and mathematics; (2) provide innovative programs, research opportunities, and mentorship to stimulate and nurture students' interest in science and research; (3) produce publications and informational articles on educational topics for broader audiences; and (4) encourage students to pursue further training for future biomedical careers.

杰克逊心脏研究（JHS）是对非裔美国人人口进行的CVD的最大调查，是在杰克逊，密西西比州大都会，麦迪逊和兰金县的杰克逊，密西西比州大都会地区的单一前瞻性流行病学研究。 JHS由国立卫生研究院（NIH）的国家心脏，肺和血液研究所（NHLBI）和美国国家少数民族健康与健康差异（NIMHD）赞助。 JHS最初是在三个当地机构之间的合作伙伴关系：杰克逊州立大学，据陶氏学院和密西西比大学医学中心，并招募了35至84岁的5306名非裔美国人男女。为了允许对CVD的家庭和遗传学贡献，包括家庭成员。 The initial examination phase of the study lasted from the fall of 2000 to March 2004 and involved an extensive examination that included a series of questionnaires (dealing with lifestyle habits, medical history, medications, social and cultural factors), physical assessments (height, weight, body size, blood pressure, electrocardiogram, ultrasound measurements of the heart and arteries in the neck, and lung function) and laboratory measurements (cholesterol and other lipids,葡萄糖，与血液凝结有关的指标等）。这项研究中收集的信息包括常规风险因素以及可能与CVD有关的新或新兴因素。它还包括新的重点领域，包括疾病的早期指标，遗传学，社会文化影响，例如社会经济地位和歧视，以及高血压，肥胖和糖尿病等常见疾病之间的生理关系及其对CVD的影响。考试2是在2005年至2008年之间进行的，从2009年到2012年进行了考试3。 JHS的五个主要目的是：（1）为JHS调查人员提供专门的时间进行数据分析并使用收集的JHS数据的财富进行手稿； （2）促进学习资源和专业知识的访问：（a）与JHS以外的研究人员一起对现有数据进行协作分析以生成高质量的出版物； （b）作为本科和研究生以及早期职业调查人员的培训理由，以帮助减轻少数族裔生物医学研究人员的短缺； and (c) serve as a platform for ancillary studies; （3）与参与者进行年度访谈，以确定临时住院和门诊就诊，传达有关JHS的信息，并作为辅助辅助研究的工具； （4）继续临床事件识别，调查和验证，以提高风险预测和假设检验的统计能力； （5）进行社区健康教育活动，以在杰克逊社区传播健康促进和预防信息。 JHS研究生培训和教育中心（GTEC）有四个目标，可以帮助JHS实现其一般所有目标，尤其是上面列出的AIM 2B。 GTEC的四个目标是：（1）加强参与学生对科学和数学知识的基础； （2）提供创新的计划，研究机会和指导，以刺激和培养学生对科学和研究的兴趣； （3）制作有关更广泛受众的教育主题的出版物和信息文章； （4）鼓励学生对未来的生物医学职业进行进一步的培训。