NONSTANDARD MODELS FOR STUDY OF COGNITIVE ERPS

研究认知 ERPS 的非标准模型

• 批准号: 2265754
• 负责人: THEODORE H BULLOCK
• 金额: $ 13.78万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN DIEGO
• 依托单位国家: 美国
• 财政年份: 1988
• 资助国家: 美国
• 起止时间: 1988-05-01 至 1998-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2265754
• 关键词: NONSTANDARD; MODELS; STUDY; COGNITIVE; ERPS

DESCRIPTION (Investigator's Abstract): Certain brain potentials can be seen or averaged out of the brain waves, time-locked to events which in humans are associated with a thought, a question, an expectation met or not met. a surprise or-a recognition; these will be called cognitive event-related potentials (ERPs). The long- term objective is to understand these relatively high level Ems in the light of comparative studies and evolution. The specific aims are to find such ElRPs in selected species of non- mammalian vertebrates (elasmobranchs, bony fish) and invertebrates (crustaceans and cephalopods), using various stimulus paradigms adapted to them, to determine their dynamic properties with permutations of the temporal patterns of rare and common stimuli of greater or lesser ethological valence, to estimate the dependence on exogenous variables (physical aspects of stimuli) vs endogenous factors (brain state variables), and-to discover the brain regions involved. The research design is to employ multiple electrodes on and in the brain in behaving subjects, wideband amplifiers to record both spike and low wave activity, single sweep and averaged sweep display, and old and new methods of analysis of data. The latter includes, firstly, distribution of coherence between all possible pairs of loci, in space and time, at new levels of resolution, millimeters and fractions of a second. Secondly, the higher moments of nonlinear cooperativity will be measured by computing the bispectrum and bicoherence, revealing quadratic phase coupling between frequency components both within the same channel and between channels.

描述(研究人员摘要)：某些大脑潜力可以 从脑电波中看到或平均出来，时间锁定在事件中 人类与一种思想、一个问题、一种满足的期望或 没见过面。一种惊喜或-一种认可；这些将被称为认知 事件相关电位(ERPs)。长期目标是 从比较的角度来理解这些相对较高级别的EMS 研究和进化。 具体目标是在选定的非生物物种中找到这种ELRP 哺乳类脊椎动物(脊椎动物、硬骨鱼)和无脊椎动物 (甲壳类和头足类)，采用不同的刺激模式 的排列来确定它们的动态属性 较大或较小的罕见和常见刺激的时间模式 行为学效价，估计对外生变量的依赖 (刺激的生理方面)与内源性因素(大脑状态 变量)，以及-发现相关的大脑区域。 研究设计是在大脑和大脑中使用多个电极 在行为受试者中，用于记录尖峰和低峰的宽带放大器 波活动、单次扫描和平均扫描显示，以及新旧 数据分析方法。后者首先包括分配 所有可能的轨迹对在空间和时间上的连贯性，在 新的分辨率级别，毫米和零点几秒。 其次，将测量非线性协作性的高阶矩。 通过计算双谱和双相干，揭示了二次相 同一信道内的频率分量之间的耦合以及 在频道之间。