CONFERENCE--CHEMOKINES IN LEUKOCYTE TRAFFICKING /DISEASE

会议——白细胞贩运/疾病中的趋化因子

• 批准号: 2005474
• 负责人: STEPHEN W HUNT
• 金额: $ 0.25万
• 依托单位: KEYSTONE CENTER
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-03-28 至 1998-03-27
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2005474
• 关键词: biological signal transduction; cell migration; chemokine; cytokine receptors; meeting /conference /symposium; travel

Chemokines are a superfamily of chemoattractant proteins that play a key role in leukocyte trafficking, and have been linked to a variety of acute and chronic inflammatory processes. The field of chemokine research has grown dramatically over the past several years. Recent advances in molecular genetics have led to the discovery of a variety of novel chemokine and chemokine receptors. Basic studies have begun to evaluate chemokine and chemokine receptor structure- function, as well as pathways used in chemokine in disease through the use of in vivo models. Finally, numerous pharmaceuticals have begun to examine chemokines as potential therapeutic targets. The aim of this meeting is to bring together experts in this, and related fields, to discuss recent advances and evaluate to role of chemokines in human disease. Topics for plenary sessions, workshops and poster sessions include: leukocyte trafficking, novel chemokines and receptors, structure-function, signal transduction, in vivo models, and therapeutics.

趋化因子是趋化蛋白的超家族，其作用是 在白细胞运输中发挥关键作用，并与多种 急性和慢性炎症过程。 趋化因子领域 研究在过去几年中急剧增长。 最近的 分子遗传学的进步导致了多种新发现 新型趋化因子和趋化因子受体。 基础研究有 开始评估趋化因子和趋化因子受体结构- 功能以及疾病中趋化因子使用的途径 使用体内模型。 终于，众多药品开始上市 检查趋化因子作为潜在的治疗靶点。 此举的目的 会议旨在汇集该领域及相关领域的专家， 讨论最新进展并评估趋化因子在人类中的作用 疾病。 全体会议、研讨会和海报会议的主题 包括：白细胞运输、新型趋化因子和受体、 结构-功能、信号转导、体内模型和 疗法。