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DEVELOPMENT AND MORTALITY OF IXODES DAMMINI

DAMMINI IXODES 的发生和死亡率

基本信息

批准号：
2003730
负责人：
Gary Smith
金额：
$ 18.76万
依托单位：
UNIVERSITY OF PENNSYLVANIA
依托单位国家：
美国
项目类别：
财政年份：
1994
资助国家：
美国
起止时间：
1994-01-01 至 1997-12-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/2003730
关键词：
Ixodes Lyme disease Peromyscus animal colony animal mortality animal population density egg /ovum epizootiology field study humidity immature animal laboratory rabbit larva mathematical model mature animal model design /development temperature

项目摘要

Lyme disease is now the most common tick borne disease in the United States. Currently, disease prophylaxis has centered mainly on education programs and the personal use of acaricides and repellents on clothing. A number of other strategies have been suggested, many of them involving attempts to reduce tick population abundance. However, the effort is by no means straight forward. Strategies for the management of several tick borne diseases on man and domestic animals benefit from the insights of a considerable theoretical literature on the ecology of the tick species involved. A comparable literature for Ixodes dammini, the tick vector of Lyme borreliosis, does not yet exist and this hampers a priori evaluation of plausible control strategies. We propose to construct a mathematical model for the population biology of I. dammini. This model is the first and essential step in the construction of a useful model for the epizootiology of Lyme borreliosis to be used in the evaluation and development of disease control strategies. The modelling process is predicated upon the measurement of certain critical life-table parameters. We propose to measure the development and mortality of eggs, larvae, nymphs and unfed adults in the laboratory and in the field. We further propose to examine putative mechanisms for the regulation of tick population density. The formal structure of the model will be based on the outcome of the laboratory measures of stage development and survival. The first round of field studies will be used to amend that formal structure so that it more closely mimics events in the field. the second round of field studies will be used to text the adequacy of the model so derived.

莱姆病现在是美国最常见的扁虱传播疾病。各州。目前，疾病预防主要集中在教育上。计划以及个人在衣服上使用杀螨剂和驱虫剂。一个已经提出了许多其他战略，其中许多涉及试图减少扁虱种群的数量。然而，这一努力绝不是意思是笔直向前。几种扁虱的管理策略人类和家畜上的传染病受益于一种相当多关于硬体动物生态的理论文献牵涉其中。达米尼硬蜱的一个可比文献，它是伊蚊的媒介莱姆疏螺旋体病尚不存在，这阻碍了先验评估看似合理的控制策略。我们建议建立一个种群生物学的数学模型我是达米尼。这一模型是构建有用的莱姆型疏螺旋体病流行病学模型的建立评估和制定疾病控制战略。造型流程是以某些关键寿命表的测量为基础的参数。我们建议测量卵、幼虫、实验室和田间的若虫和食不果腹的成虫。我们进一步建议研究可能的机制，以规管扁虱种群密度。模型的正式结构将基于阶段发育和存活的实验室测量。第一轮实地研究将用于修订正式的结构，以便它更接近地模拟该字段中的事件。第二个将使用一轮实地研究来验证该模型的充分性，以便派生的。