DEVELOPMENT AND MORTALITY OF IXODES DAMMINI

DAMMINI IXODES 的发生和死亡率

• 批准号: 2066955
• 负责人: Gary Smith
• 金额: $ 16.56万
• 依托单位: UNIVERSITY OF PENNSYLVANIA
• 依托单位国家: 美国
• 财政年份: 1994
• 资助国家: 美国
• 起止时间: 1994-01-01 至 1997-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2066955
• 关键词: Ixodes; Lyme disease; Peromyscus; animal colony; animal mortality; animal population density; egg /ovum; epizootiology; field study; humidity; immature animal; laboratory rabbit; larva; mathematical model; mature animal; model design /development; temperature

Lyme disease is now the most common tick borne disease in the United States. Currently, disease prophylaxis has centered mainly on education programs and the personal use of acaricides and repellents on clothing. A number of other strategies have been suggested, many of them involving attempts to reduce tick population abundance. However, the effort is by no means straight forward. Strategies for the management of several tick borne diseases on man and domestic animals benefit from the insights of a considerable theoretical literature on the ecology of the tick species involved. A comparable literature for Ixodes dammini, the tick vector of Lyme borreliosis, does not yet exist and this hampers a priori evaluation of plausible control strategies. We propose to construct a mathematical model for the population biology of I. dammini. This model is the first and essential step in the construction of a useful model for the epizootiology of Lyme borreliosis to be used in the evaluation and development of disease control strategies. The modelling process is predicated upon the measurement of certain critical life-table parameters. We propose to measure the development and mortality of eggs, larvae, nymphs and unfed adults in the laboratory and in the field. We further propose to examine putative mechanisms for the regulation of tick population density. The formal structure of the model will be based on the outcome of the laboratory measures of stage development and survival. The first round of field studies will be used to amend that formal structure so that it more closely mimics events in the field. the second round of field studies will be used to text the adequacy of the model so derived.

莱姆病现在是曼联最常见的tick虫传播疾病 国家。目前，预防疾病主要集中于教育 程序以及对服装上的丙酰胺和驱虫剂的个人使用。一个 已经提出了许多其他策略，其中许多涉及 试图减少壁虱人口丰度。但是，努力是没有 意味着直截了当。管理几个壁虱的策略 关于人和家畜的传播疾病受益于 关于壁虱物种生态学的大量理论文献 涉及。 ixodes Dammini的可比文献，tick矢量 莱姆毛毛虫病尚不存在，这阻碍了先验评估 合理的控制策略。 我们建议为人口生物学构建数学模型 I. Dammini。 该模型是构建有用的第一步 用于用于莱姆毛毛虫病的表育动物学的模型 评估和发展疾病控制策略。建模 过程是基于某些关键生命表的测量 参数。 我们建议衡量卵，幼虫的发育和死亡率， 实验室和野外的若虫和未成年的成年人。 我们进一步建议检查假定的机制以调节 滴答种群密度。 模型的形式结构将基于 舞台发展和生存的实验室措施。 第一轮研究将用于修改正式 结构使其更紧密地模仿该领域的事件。第二个 一轮野外研究将用于对模型的充分性发短信 衍生的。