Prototype development for sustained release amino acid supplement in horses

我们的项目目标是将微胶囊技术(基质颗粒技术或核壳胶囊)应用于一个新的领域，以开发一种用于马的功能性氨基酸β-丙氨酸的创新口服给药系统。这一创新将提高我们现有的贝塔丙氨酸产品STORM®的附加值。我们的目标是从马的消化道实现持续的β丙氨酸吸收，以保持和延长血液中有益的浓度，这反过来将改善体内的滞留(生物利用度)，从而增强其生化功能和功效。我们将把新技术转移到一个新的领域：专业动物饲料的生产。这项优化用于马的技术也可以应用于其他单胃和反刍动物，为开发专业饲料和药物以及用于猪和肉牛的农业部门提供潜在应用，以改善肉类质量。该项目的成功完成将使我们能够将我们的“新改进”风暴产品推向美国更主要的产品市场，具有更强的有效性和更长的保质期/稳定性。这将极大地改善我们的国内销售，我们对那些我们在那里建立了分销商的国家的出口，并将促进向新市场的扩张，拥有蓬勃发展的赛车行业，如日本和印度。该项目与我们的两个商业技术合作伙伴一起实现的业务扩张将增加就业机会，特别是在农村地区，并将为英国的收支平衡做出贡献。BHIC报告称，骑马在英国现在比橄榄球、钓鱼和板球更受欢迎。我们的新产品代表了马术运动营养方面的前沿进步，提供了对细节的关注，这对于我们的马术队在2012年伦敦奥运会上取得成功并保持在全球舞台的前沿至关重要。

Our project objective is to apply microencapsulation technology (matrix particle techniques or core shell encapsulation) in a new sector to develop an innovative oral delivery system for a functional amino acid beta alanine for horses. This innovation will improve add value to our existing beta alanine product STORM®. We aim to achieve sustained beta alanine absorption from the horses’ digestive tract to maintain and prolong a beneficial concentration in the blood, which in turn will improve retention (bioavailability) in the body thus enhancing itsbiochemical functionality and efficacy. We will be transferring novel technology to a new area: production of specialist animal feeds.This technology optimised for use in horses can be applied for other monogastric andruminant animals offering potential applications for the development of specialist feedingredients and medicines and use in the agricultural sector for pigs and beef cattle, toimprove meat quality.Successful completion of the project will enable us to market our ‘New improved’ STORM product with further major USPs, with strong evidence of enhanced efficacy, and improved shelf life/stability. This will dramatically improve our domestic sales, our exports to those countries where in we have established distributors, and will enhance expansion into new markets with thriving racing industries such as Japan and India. Our business expansion resulting from this project in conjunction with our two business technology partners will increase jobs particularly in rural areas and will contribute to the UK’s balance of payments.The BHIC report that horse riding is now more popular in the UK than rugby, fishing, orcricket. Our new product represents a cutting edge advance in equine sports nutrition offering the attention to detail that is essential to build upon the success of our equestrian teams at the London 2012 Olympics and to keep them at the front of the global stage.