Evolution of the marsupial gut microbiome and adaptation to eucalypt toxins

点击翻译按钮获取中文摘要

Eucalyptus leaves comprise all or part of the diet of some marsupials including koalas. Gut microbiota assist in the ability of these folivores to tolerate eucalyptus toxins although present understanding of this process is rudimentary. This project aims to use culture-independent molecular methods to identify and characterise gut populations involved in phytochemical detoxification by comparative analysis with diprotodont relatives that are not capable of digesting eucalyptus leaves. This will highlight evolutionary convergence of gut microbiomes in toxic folivores and reveal mechanisms by which microorganisms respond to and metabolise eucalypt toxins. A broader evolutionary context of marsupial digestive function will assist in ongoing conservation efforts.