NOVEL CORROSION RESISTANT BIOACTIVE SURGICAL IMPLANTS

新型耐腐蚀生物活性手术植入物

• 批准号: 2007035
• 负责人: ZORAN S MINEVSKI
• 金额: $ 10万
• 依托单位: LYNNTECH, INC.
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-09-01 至 1998-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2007035
• 关键词: atomic force microscopy; biomaterial compatibility; biomaterial development /preparation; corrosions; electrochemistry; hydroxyapatites; implant; molecular film; phosphates; photoelectron spectrometry; surgery material /equipment; titanium

This small business innovation research Phase I project is concerned with the design and development of new titanium surgical implants with highly corrosion resistant and wear stabilized surfaces. A novel electrochemical method will be used for the preparation of phosphated titanium oxide. The method involves direct electrochemical deposition of novel titanium-phosphate corrosion barrier by anodic oxidation of titanium in phosphoric acid at near ambient temperatures. The proposed Phase I research effort will be utilized to design a cost effective method for production of corrosion resistant bioactive surgical implants. The benefits of electrochemical deposition of titanium phosphate corrosion/wear barrier are: (I) high corrosion resistance, (ii) excellent antiwear properties and (iii) similar or lower production cost due to minimal needs of capital investment for proposed procedures. Briefly, in Phase I, research will be carried out to investigate critical issues related to the electrochemical deposition of titanium-phosphate protective coatings, on titanium surgical alloys, and to characterize the corrosion and wear performance. PROPOSED COMMERCIAL APPLICATION: The commercial need for corrosion and wear resistant bioactive surgical implants is remarkably large. In the U.S., alone 400,000 artificial implants were employed in 1993. This increased use of prostheses is the result of continually increasing life span. The technology developed in this research project will be of considerable benefit to the medical field. The relatively low capital cost and environmentally friendly nature of the proposed method makes it suitable for use even in small medical or dental clinics.

此次小企业创新研究一期项目所关注 设计和开发新型钛手术植入物 高度耐腐蚀和耐磨稳定的表面。 一本小说 采用电化学方法制备磷酸盐 氧化钛。 该方法涉及直接电化学沉积 新型钛磷酸盐腐蚀屏障的阳极氧化 在接近环境温度的磷酸中钛。 拟议的第一阶段研究工作将用于设计成本 一种生产耐腐蚀生物活性手术材料的有效方法 植入物。 电化学沉积钛的优点 磷酸盐腐蚀/磨损屏障具有：(I) 高耐腐蚀性，(ii) 优异的抗磨损性能和 (iii) 类似或更低的生产成本 由于拟议程序的资本投资需求极小。 简而言之，在第一阶段，将进行研究以调查关键的 磷酸钛电化学沉积的相关问题 钛手术合金上的保护涂层，并表征 腐蚀和磨损性能。 拟议的商业应用：商业需求 耐腐蚀、耐磨损的生物活性外科植入物具有显着的优势 大的。仅在美国，就使用了 400,000 个人工植入物 1993. 假肢使用的增加是持续不断的结果 增加寿命。本研究项目开发的技术 将为医疗领域带来巨大的好处。相对较低的 拟议项目的资本成本和环境友好性 方法使其即使在小型医疗或牙科中也适用 诊所。