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MOLECULAR MARKERS OF HUMAN LIVER CANCER-NOVEL GENES DIFFERENTIALLY EXPRESSED

MOLECULAR MARKERS OF HUMAN LIVER CANCER-NOVEL GENES DIFFERENTIALLY EXPRESSED
人类肝癌的分子标记——差异表达的新基因
批准号：
2463681
负责人：
J A LAUTENBERGER
金额：
$0.0万
依托单位：
DIVISION OF BASIC SCIENCES - NCI
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/2463681
关键词：
gene expression genetic markers human genetic material tag human tissue liver neoplasms messenger RNA molecular oncology neoplasm /cancer genetics northern blottings polymerase chain reaction tissue /cell culture

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中文摘要
翻译
RNA差异显示分析使用来自 肝癌细胞株SK-Hep-1、Hep-G2、Hep-3B及正常对照 肝脏RNA。从凝胶中洗脱出有希望的条带，并从分子上 克隆的。大约有20个克隆被证实对应于 用RNA凝胶对不同来源的RNA进行差异表达 (北方)吸墨法。探测多组织Northern(MTN)印迹 揭示了这些基因中的几个在正常情况下表达有限 纸巾。它们在肝脏生物学研究中可能是有用的。 癌症或可能是这种疾病的潜在标志。
英文摘要
A RNA differential display analysis was performed using RNAs from the liver tumor cell lines SK-HEP-1, HEP-G2 and HEP-3B, as well as normal liver RNA. Promising bands were eluted from the gel and molecularly cloned. About 20 clones were confirmed to correspond to genes that are differentially expressed among the different RNA sources by RNA gel (Northern) blotting. Probing multiple tissue Northern (MTN) blots revealed that several of these genes have limited expression in normal tissues. They may be useful in the study of the biology of liver cancer or may be potential markers for this disease.
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会议论文
IDENTIFICATION OF MOLECULAR MARKERS FOR HUMAN LUNG CANCER
ANTISENSE OLIGONUCLEOTIDES AS INHIBITORS OF TUMOR-INDUCED ANGIOGENESIS
DETECTION OF LINKAGE DISEQUILIBRIUM IN AFRICAN AMERICANS NEAR THE FY GENE
  • 批准号：
    6161151
  • 项目类别：
  • 资助金额：
    $0.0万
  • 财政年份：
    --
  • 负责人：
    J A LAUTENBERGER
  • 依托单位：
    DIVISION OF BASIC SCIENCES - NCI
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