APPLICATION OF FLOW CYTOMETRY TO CELL BIOLOGY

实验免疫学分院流式细胞仪实验室 支持40多名研究人员的多个研究项目。 这些研究包括定量的单细胞分析，以及 基于与电池相关的参数的电子电池分离 从不同物种和/或组织新鲜制备的，以及 体外培养细胞的光谱。基础研究支持是 提供给欧洲投资银行成员和星展银行内的其他调查人员。 目前支持的项目包括但不限于 以下研究领域：a)体内和体外分析 通过T细胞表面分子的细胞内信号传递；b)分析 遗传缺陷动物的细胞过程和/或缺陷 修改；c)移植物抗宿主的发病机制研究 D)细胞表面配位表达的分析 黏附分子；e)T细胞谱系生成的研究； G)分析移植抗原的表达情况；h) 抗原提呈机制的研究 过程；以及i)分析骨髓移植所涉及的机制 拒绝与接受。

The Experimental Immunology Branch flow cytometry laboratory currently supports multiple research projects for more than 40 investigators. These investigations involve quantitative single cell analysis of, and electronic cell separation based upon, parameters associated with cells freshly prepared from different species and/or tissues, as well as a spectrum of in vitro cultured cells. Basic research support is provided to members of the EIB and to other investigators within DBS. Currently supported projects include, but are not limited to, the following areas of study: a) in vivo and in vitro analyses of intra-cellular signaling via T cell surface molecules; b) analyses of cellular processes and/or defects in animals with genetic modifications; c) studies of the pathogenesis of graft-versus host disease; d) analyses of the coordinate cell surface expression of cell adhesion molecules; e) investigations of T cell repertoire generation; g) analyses of expression of transplantation antigens; h) investigations of mechanisms involved in antigen presentation processes; and i) analyses of the mechanisms involved in marrow graft rejection versus acceptance.