APPLICATION OF FLOW CYTOMETRY TO CELL BIOLOGY

实验免疫学分院流式细胞仪实验室 支持40多名研究人员的多个研究项目。 这些研究涉及多参数定量单细胞 参数分析和基于参数的电子单元分离 与新鲜从不同物种和/或 组织，以及体外培养细胞的光谱。基本信息 向欧洲投资银行的成员和其他人提供研究支持 星展银行内部的调查人员。目前支持的项目包括，但 A)体内和体外研究 通过T细胞表面分子分析细胞内信号；b) 遗传缺陷动物的细胞过程和/或缺陷分析 修改；c)移植物抗宿主的发病机制研究 D)细胞表面配位表达的分析 黏附分子；e)T细胞谱系生成的研究； G)分析移植抗原的表达情况；h)调查 抗原呈递过程中涉及的机制；以及i) 骨髓移植排斥反应的机制分析 接受。

The Experimental Immunology Branch flow cytometry laboratory currently supports multiple research projects for more than 40 investigators. These investigations involve multiparametric quantitative single cell analysis of, and electronic cell separation based upon, parameters associated with cells freshly prepared from different species and/or tissues, as well as a spectrum of in vitro cultured cells. Basic research support is provided to members of the EIB and to other investigators within DBS. Currently supported projects include, but are not limited to, the following areas of study: a) in vivo and in vitro analyses of intra-cellular signaling via T cell surface molecules; b) analyses of cellular processes and/or defects in animals with genetic modifications; c) studies of the pathogenesis of graft-versus host disease; d) analyses of the coordinate cell surface expression of cell adhesion molecules; e) investigations of T cell repertoire generation; g) analyses of expression of transplantation antigens; h) investigations of mechanisms involved in antigen presentation processes; and i) analyses of the mechanisms involved in marrow graft rejection versus acceptance.