PULMONARY INFECTION IN PATIENTS WITH CHRONIC GRANULOMATOUS DISEASE (CGD)

慢性肉芽肿病 (CGD) 患者的肺部感染

• 批准号: 2456662
• 负责人: F P OGNIBENE
• 金额: --
• 依托单位: CLINICAL CENTER
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/2456662
• 关键词: artificial intelligence; biopsy; bronchoscopy; chronic granulomatous disease; clinical research; diagnosis design /evaluation; diagnosis quality /standard; fine needle aspiration; human subject; opportunistic infections; respiratory disorder diagnosis; respiratory infections; secondary infection; sputum

Patients with chronic granulomatous disease (CGD) frequently develop pulmonary infections. In many patients, an accurate diagnosis is difficult to establish because of the scarcity of organisms in pathologic specimens. This retrospective study assesses all procedural as well as diagnostic data in patients with CGD and pulmonary disease. The study assesses the utility of sputum, bronchoscopy (lavage and transbronchial biopsy), CTT-guided transthoracic needle aspiration, and open lung biopsy in establishing either a definitive or a presumptive pulmonary diagnosis. The goal is to establish a diagnostic algorithm for pulmonary procedures based on relative invasiveness and diagnostic yield. Data are being collected for analysis.

慢性肉芽肿病（CGD）患者经常发生 肺部感染在许多患者中，准确的诊断是 由于缺乏有机体， 病理标本 这项回顾性研究评估了所有手术以及 CGD和肺部疾病患者的诊断数据。的 一项研究评估了痰液、支气管镜检查（灌洗和 经支气管活检），CT引导下经胸针吸， 和开放性肺活检，以建立一个明确的或 推定肺部诊断。目标是建立 基于相关性的肺部手术的诊断算法 入侵性和诊断率。正在收集数据， 分析.