DEVICE TO MEASURE BODY VOLUME AND COMPOSITION IN INFANTS

拟议研究的目标是开发和评估一部小说 婴幼儿身体体积和成分的测量方法。身体成分 (脂肪和脱脂质量百分比)信息在评估中非常重要 营养状况和生长情况。鉴于目前缺乏任何合适的 技术为此目的，研究人员和临床医生无法访问 这些有价值的信息。拟议的方法一直是 成功地开发并应用于成年人口，并已 产生了一种商业上成功的设备，销往大学和 其他对医疗保健感兴趣的客户。技术的延伸 由于特殊的考虑，对婴儿来说尤其具有挑战性 这是针对这一年轻群体的特殊要求。尤其是高 有意义的身体组成所需的精密度和准确度 对非常小的婴儿进行检测是令人望而生畏的。申请人 组织在这一领域经验丰富，并已证明 第一阶段工程样机的出色效果。建议数 第二阶段的研究将涉及实质性的技术开发，特别是 应用于婴儿群体，与科学的互动 专门针对该项目的咨询委员会，并在一个步骤中进行彻底评估- 智慧的时尚从无生命的幻象开始，逐渐演变为动物， 最后，还有婴儿。 建议的商业应用： 这项拟议的研究可能会导致一部完整的小说的发展 婴幼儿身体成分测量方法的研究和应用 参与婴儿营养评估和生长发育的医生。AS 医疗技术进步，婴儿在较低的温度下存活越来越多 出生体重，产生了更大的需要监测身体的脂肪和瘦 组织。

The goal of the proposed research is to develop and evaluate a novel method of infant body volume and composition measurement. Body composition (% fat and fat-free mass) information is very important in the assessment of nutritional status and growth. Given the current lack of any suitable technology for this purpose, researchers and clinicians do not have access to this valuable information. The proposed methodology has been successfully developed and applied to the adult population, and has resulted in a commercially successful device marketed to universities and other customers interested in health care. The extension of the technology to infants is particularly challenging due special considerations and requirements specific to this young population. In particular, the high degree of precision and accuracy required for meaningful body composition determinations in very small infants is daunting. The applicant organization is highly experienced in this area, and has demonstrated excellent results with the Phase I engineering prototype. The proposed Phase II research will involve substantial technology development, special application to the infant population, interaction with a Scientific Advisory Board specific to the project, and thorough evaluation in a step- wise fashion beginning with inanimate phantoms and progressing to animals, and, lastly, infants. PROPOSED COMMERCIAL APPLICATION: The proposed research may lead to the development of a completely novel method of infant body composition measurement useful to researchers and physicians involved in infant nutritional assessment and growth. As medical technology advances, infants are increasingly viable at lower birth weights, creating a greater need to monitor body fat and lean tissue.