REGULATION OF NUCLEAR ENVELOPE ASSEMBLY AND DISASSEMBLY
REGULATION OF NUCLEAR ENVELOPE ASSEMBLY AND DISASSEMBLY
批准号:
2630942
负责人:
Katherine L Wilson
金额:
$27.17万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
1994
资助国家:
美国
项目状态:
已结题
起止时间:
1994-05-01 至 2002-04-30
中文摘要
描述:具体目标1(项目A)的目标是认真
说明核孔组装中的中间体(使用化学分期
小麦胚芽凝集素、BAPTA和低温等试剂)和
确定促进孔隙形成的可溶因素和
稳定状态。具体目标2(项目B)的目标是测试
膜包埋核孔蛋白gp120和pom121在细胞周期调控中的作用
膜融合事件被认为是产生毛孔的原因。目标是
具体目标3(项目C)是识别和分析可溶物
核孔素在功能上显著地与
Gp120和pom 121。
英文摘要
DESCRIPTION: The goals of specific aim 1 (project A) are to carefully
state the intermediates in nuclear pore assembly (using chemical staging
reagents such as wheat germ agglutinin, BAPTA, and low temperature) and
to identify soluble factors that promote pore formation and
stabilization. The goal of specific aim 2 (project B) is to test the
roles of the membrane-embedded nucleoporins, gp120 and pom 121, in the
membrane fusion' event that is thought to generate the pore. The goal
of specific aim 3 (project C) is to identify and analyze soluble
nucleoporins that associate in a functionally significant manner with
gp120 and pom 121.
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会议论文
HopkinsPREP: Research, Community, Professional Training and Personal Growth
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批准号:10591630
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项目类别:
-
资助金额:$8.64万
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财政年份:2022
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负责人:Katherine L Wilson
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依托单位:
HopkinsPREP: Research, Community, Professional Training and Personal Growth
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批准号:10117034
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项目类别:
-
资助金额:$34.63万
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财政年份:2015
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负责人:Katherine L Wilson
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依托单位:
HopkinsPREP: Research, Community, Professional Training and Personal Growth
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批准号:10437605
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项目类别:
-
资助金额:$34.63万
-
财政年份:2015
-
负责人:Katherine L Wilson
-
依托单位:
HopkinsPREP: Research, Community, Professional Training and Personal Growth
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批准号:9052779
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项目类别:
-
资助金额:$28.01万
-
财政年份:2015
-
负责人:Katherine L Wilson
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依托单位:
HopkinsPREP: Research, Community, Professional Training and Personal Growth
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批准号:10560615
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项目类别:
-
资助金额:$34.63万
-
财政年份:2015
-
负责人:Katherine L Wilson
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依托单位:
HopkinsPREP: Research, Community, Professional Training and Personal Growth
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批准号:9417015
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项目类别:
-
资助金额:$28.01万
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财政年份:2015
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负责人:Katherine L Wilson
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依托单位:
ASCB Summer Meeting: Nuclear Architecture and Disease
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批准号:6989833
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项目类别:
-
资助金额:$0.5万
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财政年份:2005
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负责人:Katherine L Wilson
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依托单位:
Functional Analysis of LEM-domain Nuclear Proteins
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批准号:6891432
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项目类别:
-
资助金额:$26.75万
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财政年份:2002
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负责人:Katherine L Wilson
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依托单位:
Functional Analysis of LEM-domain Nuclear Proteins
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批准号:6620529
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项目类别:
-
资助金额:$26.83万
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财政年份:2002
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负责人:Katherine L Wilson
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依托单位:
Functional Analysis of LEM-domain Nuclear Proteins
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批准号:6744375
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项目类别:
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资助金额:$26.79万
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财政年份:2002
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负责人:Katherine L Wilson
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依托单位:
Functional Analysis of LEM-domain Nuclear Proteins
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批准号:6418576
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项目类别:
-
资助金额:$27.68万
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财政年份:2002
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负责人:Katherine L Wilson
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依托单位:
REGULATION OF NUCLEAR ENVELOPE ASSEMBLY AND DISASSEMBLY
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批准号:6180109
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项目类别:
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资助金额:$28.01万
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财政年份:1994
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负责人:Katherine L Wilson
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依托单位:
Regulation of Nuclear Envelope Assembly and Disassembly
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批准号:6893010
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项目类别:
-
资助金额:$2.64万
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财政年份:1994
-
负责人:Katherine L Wilson
-
依托单位:
REGULATION OF NUCLEAR ENVELOPE ASSEMBLY AND DISASSEMBLY
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批准号:2186151
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项目类别:
-
资助金额:$26.9万
-
财政年份:1994
-
负责人:Katherine L Wilson
-
依托单位:
REGULATION OF NUCLEAR ENVELOPE ASSEMBLY AND DISASSEMBLY
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批准号:2415180
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项目类别:
-
资助金额:$27.23万
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财政年份:1994
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负责人:Katherine L Wilson
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依托单位:
Regulation of nuclear envelope assembly and disassembly
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批准号:7636217
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项目类别:
-
资助金额:$48.71万
-
财政年份:1994
-
负责人:Katherine L Wilson
-
依托单位:
Regulation of nuclear envelope assembly and disassembly
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批准号:7615399
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项目类别:
-
资助金额:$51.37万
-
财政年份:1994
-
负责人:Katherine L Wilson
-
依托单位:
REGULATION OF NUCLEAR ENVELOPE ASSEMBLY AND DISASSEMBLY
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批准号:6584762
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项目类别:
-
资助金额:$9.71万
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财政年份:1994
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负责人:Katherine L Wilson
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依托单位:
Regulation of Nuclear Envelope Assembly and Disassembly
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批准号:7099634
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项目类别:
-
资助金额:$50.4万
-
财政年份:1994
-
负责人:Katherine L Wilson
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依托单位:
Regulation of nuclear envelope assembly and disassembly
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批准号:7882286
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项目类别:
-
资助金额:$52.72万
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财政年份:1994
-
负责人:Katherine L Wilson
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依托单位:
海外基金