ASCB Summer Meeting: Nuclear Architecture and Disease

ASCB 夏季会议：核结构与疾病

• 批准号: 6989833
• 负责人: Katherine L Wilson
• 金额: $ 0.5万
• 依托单位: AMERICAN SOCIETY FOR CELL BIOLOGY
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-07-01 至 2006-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6989833
• 关键词: cell component structure /function; cell nucleus; meeting /conference /symposium; travel

DESCRIPTION (provided by applicant): This meeting on Nuclear Architecture and Disease will be sponsored by the American Society for Cell Biology (ASCB). Meeting topics are proposed by ASCB members and selected by a committee based on significance, timeliness, interest and the strengths of the organizers and potential speakers. This meeting will be held at Iowa State University, Ames Iowa, on July 21-24 of 2005. It will provide a cutting-edge overview of nuclear architecture, and explore novel links between nuclear architecture and human diseases including aging, cardiovascular disease, cancer, muscular dystrophy, diabetes, skin, bone and nerve disorders. The format will stimulate interdisciplinary collaborations between basic and clinical researchers, and will feature talks both by experienced visionaries and new investigators. The meeting is expected to generate novel insights into nuclear disease mechanisms and identify key future directions. A comprehensive meeting on this topic has not previously been held, in part because most links between lamins and diseases were discovered less than 5 years ago, and because recent technical advances were required to appreciate the impact of intranuclear spatial organization on the human genome. A comprehensive meeting on nuclear architecture and disease is viewed by the cell biology community as urgent to develop this field and stimulate many related fields in basic and clinical research. The meeting will include 6 keynote talks, sessions on chromosomes and gene activity, lamins and laminopathies, intra-nuclear networks and architecture, and an entire session devoted to cutting-edge work selected from abstracts. Over 40% of the platform talks will be selected from abstracts and feature primarily young investigators. There will be poster sessions to stimulate one-on-one interactions. The format will be educational and exciting to an audience of ~200, evenly distributed between trainees and junior and senior investigators. The meeting will foster intense informal discussion in search of common principals and will stimulate interest and progress in this emerging 'post-genomic' field.

描述（由申请人提供）：这次关于核结构和疾病的会议将由美国细胞生物学协会（ASCB）主办。会议主题由ASCB成员提出，并由一个委员会根据组织者和潜在发言者的重要性，及时性，兴趣和优势进行选择。这次会议将于2005年7月21日至24日在爱荷华州艾姆斯的爱荷华州州立大学举行。它将提供核结构的前沿概述，并探索核结构与人类疾病之间的新联系，包括衰老，心血管疾病，癌症，肌肉萎缩症，糖尿病，皮肤，骨骼和神经疾病。该形式将刺激基础和临床研究人员之间的跨学科合作，并将由经验丰富的远见者和新研究人员进行演讲。预计会议将产生对核疾病机制的新见解，并确定未来的主要方向。关于这一主题的全面会议以前没有举行过，部分原因是核纤层蛋白和疾病之间的大多数联系是在不到5年前发现的，并且因为需要最近的技术进步来了解核内空间组织对人类基因组的影响。细胞生物学界认为，一个关于核结构和疾病的全面会议是发展这一领域并刺激基础和临床研究中许多相关领域的迫切需要。会议将包括6个主题演讲，关于染色体和基因活性，核纤层蛋白和核纤层蛋白病，核内网络和架构的会议，以及一个专门讨论从摘要中选出的尖端工作的整个会议。超过40%的平台演讲将从摘要中选出，主要是年轻的研究人员。将有海报会议，以刺激一对一的互动。该格式将是教育和令人兴奋的观众约200，平均分布在学员和初级和高级调查员。会议将促进激烈的非正式讨论，以寻求共同的原则，并将激发人们对这一新兴的“后基因组”领域的兴趣和进展。