课题基金 / 基金详情

REGULATION OF NUCLEAR ENVELOPE ASSEMBLY AND DISASSEMBLY

REGULATION OF NUCLEAR ENVELOPE ASSEMBLY AND DISASSEMBLY
核壳组装和拆卸的规定
批准号：
6584762
负责人：
Katherine L Wilson
金额：
$9.71万
依托单位：
JOHNS HOPKINS UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
1994
资助国家：
美国
项目状态：
已结题
起止时间：
1994-05-01 至 2003-04-30
来源：
https://reporter.nih.gov/project-details/6584762
关键词：
Xenopus oocyte biological signal transduction glycoproteins laboratory mouse laboratory rabbit laboratory rat membrane biogenesis membrane fusion membrane proteins nuclear membrane phosphorylation protein structure function receptor binding scanning electron microscopy

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中文摘要
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英文摘要
DESCRIPTION: The goals of specific aim 1 (project A) are to carefully state the intermediates in nuclear pore assembly (using chemical staging reagents such as wheat germ agglutinin, BAPTA, and low temperature) and to identify soluble factors that promote pore formation and stabilization. The goal of specific aim 2 (project B) is to test the roles of the membrane-embedded nucleoporins, gp120 and pom 121, in the membrane fusion' event that is thought to generate the pore. The goal of specific aim 3 (project C) is to identify and analyze soluble nucleoporins that associate in a functionally significant manner with gp120 and pom 121.
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HopkinsPREP: Research, Community, Professional Training and Personal Growth
  • 批准号：
    10591630
  • 项目类别：
  • 资助金额：
    $8.64万
  • 财政年份：
    2022
  • 负责人：
    Katherine L Wilson
  • 依托单位：
    JOHNS HOPKINS UNIVERSITY
HopkinsPREP: Research, Community, Professional Training and Personal Growth
  • 批准号：
    10117034
  • 项目类别：
  • 资助金额：
    $34.63万
  • 财政年份：
    2015
  • 负责人：
    Katherine L Wilson
  • 依托单位：
    JOHNS HOPKINS UNIVERSITY
HopkinsPREP: Research, Community, Professional Training and Personal Growth
  • 批准号：
    10437605
  • 项目类别：
  • 资助金额：
    $34.63万
  • 财政年份：
    2015
  • 负责人：
    Katherine L Wilson
  • 依托单位：
    JOHNS HOPKINS UNIVERSITY
HopkinsPREP: Research, Community, Professional Training and Personal Growth
  • 批准号：
    9052779
  • 项目类别：
  • 资助金额：
    $28.01万
  • 财政年份：
    2015
  • 负责人：
    Katherine L Wilson
  • 依托单位：
    JOHNS HOPKINS UNIVERSITY
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