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COXOFEMORAL JOINT MODIFICATION TO PREVENT HIP DYSPLASIA

COXOFEMORAL JOINT MODIFICATION TO PREVENT HIP DYSPLASIA
髋股关节改造以预防髋关节发育不良
批准号:
2708413
负责人:
MANDI J. LOPEZ
金额:
$3.41万
依托单位国家:
美国
项目类别:
财政年份:
1999
资助国家:
美国
项目状态:
未结题
起止时间:
1999-02-16 至

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中文摘要
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英文摘要
The goals of this fellowship program are to develop a method for early stabilization of the coxofemoral joint using radio-frequency energy to permit normal development and prevent the clinical manifestations of canine hip dysplasia. The pathology of developmental dysplasia of the hip in children is very similar to the canine version. Ultimately, this research will lead to the establishment of an animal model of radio- frequency treatment of developmental dysplasia of the hip in children. This project will involve the application of radio-frequency energy to the coxofemoral joint capsule of the puppies determined by established radiographic methods to be predisposed to the development of hip dysplasia. Computed tomography will also be used to determine the conformation of the joint. The progression of the disease will then be monitored with radiographs, computed tomography, histology, electron microscopy, joint fluid analysis, and force plate evaluation over a period of two years. Treated animals will be compared to untreated controls. This project will provide an in depth analysis of the progression of canine hip dysplasia in untreated animals and the inhibition of its progression in those treated with radio-frequency.
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