COXOFEMORAL JOINT MODIFICATION TO PREVENT HIP DYSPLASIA
COXOFEMORAL JOINT MODIFICATION TO PREVENT HIP DYSPLASIA
批准号:
6171572
负责人:
MANDI J. LOPEZ
金额:
$4.63万
依托单位国家:
美国
项目类别:
财政年份:
2000
资助国家:
美国
项目状态:
未结题
起止时间:
2000-09-01 至
中文摘要
该奖学金计划的目标是开发一种早期治疗的方法。
利用射频能量稳定髋股关节
允许正常发育,并防止临床表现
犬类髋关节发育不良。发育性髋关节发育不良的病理学研究
在儿童中的版本非常类似于狗的版本。归根结底,这
研究将导致建立无线电的动物模型-
儿童发育性髋关节发育不良的频率治疗。
该项目将涉及将射频能量应用于
已建立的幼犬髋股关节囊的测定
易发生髋关节病变的X线检查方法
发育不良。计算机断层扫描也将被用来确定
关节的构象。疾病的发展将会是
使用X光照片、计算机断层扫描、组织学、电子技术进行监控
显微镜检查、关节液分析和一段时间内的测力板评估
已经两年了。经过处理的动物将与未经处理的对照组进行比较。这
该项目将对犬类髋关节的进展进行深入分析
未经治疗的动物异型增生及其进展的抑制
那些接受射频治疗的人。
英文摘要
The goals of this fellowship program are to develop a method for early
stabilization of the coxofemoral joint using radio-frequency energy to
permit normal development and prevent the clinical manifestations of
canine hip dysplasia. The pathology of developmental dysplasia of the hip
in children is very similar to the canine version. Ultimately, this
research will lead to the establishment of an animal model of radio-
frequency treatment of developmental dysplasia of the hip in children.
This project will involve the application of radio-frequency energy to the
coxofemoral joint capsule of the puppies determined by established
radiographic methods to be predisposed to the development of hip
dysplasia. Computed tomography will also be used to determine the
conformation of the joint. The progression of the disease will then be
monitored with radiographs, computed tomography, histology, electron
microscopy, joint fluid analysis, and force plate evaluation over a period
of two years. Treated animals will be compared to untreated controls. This
project will provide an in depth analysis of the progression of canine hip
dysplasia in untreated animals and the inhibition of its progression in
those treated with radio-frequency.
期刊论文(4)
专著(0)
科研奖励(0)
会议论文
Acceleration of spinal fusion using syngeneic and allogeneic adult adipose derived stem cells in a rat model.
在大鼠模型中,使用同种异体和同种异体成年脂肪衍生的干细胞加速脊柱融合。
DOI:
10.1002/jor.20735
发表时间:
2009-03
期刊:
JOURNAL OF ORTHOPAEDIC RESEARCH
影响因子:
2.8
作者:
[Lopez, Mandi J., McIntosh, Kevin R., Spencer, Nakia D., Borneman, Jade N., Horswell, Ronald, Anderson, Paul, Yu, Gang, Gaschen, Lorrie, Gimble, Jeffrey M.]
通讯作者:
Gimble, Jeffrey M.
Pre-Clinical Evaluation Core
-
批准号:10360593
-
项目类别:
-
资助金额:$37.22万
-
财政年份:2021
-
负责人:MANDI J. LOPEZ
-
依托单位:
Pre-Clinical Evaluation Core
-
批准号:10579204
-
项目类别:
-
资助金额:$33.64万
-
财政年份:2021
-
负责人:MANDI J. LOPEZ
-
依托单位:
ADULT STEM CELL SUPPRESSION DUE TO ALCOHOL INDUCED MICROENVIRONMENT ALTERATIONS
-
批准号:7458223
-
项目类别:
-
资助金额:$22.05万
-
财政年份:2008
-
负责人:MANDI J. LOPEZ
-
依托单位:
ADULT STEM CELL SUPPRESSION DUE TO ALCOHOL INDUCED MICROENVIRONMENT ALTERATIONS
-
批准号:8055095
-
项目类别:
-
资助金额:$4.7万
-
财政年份:2008
-
负责人:MANDI J. LOPEZ
-
依托单位:
Prevention of Hip Dysplasia with Thermal Energy
-
批准号:6932298
-
项目类别:
-
资助金额:$11.28万
-
财政年份:2001
-
负责人:MANDI J. LOPEZ
-
依托单位:
Prevention of Hip Dysplasia with Thermal Energy
-
批准号:6324250
-
项目类别:
-
资助金额:$10.26万
-
财政年份:2001
-
负责人:MANDI J. LOPEZ
-
依托单位:
Prevention of Hip Dysplasia with Thermal Energy
-
批准号:6645495
-
项目类别:
-
资助金额:$8.45万
-
财政年份:2001
-
负责人:MANDI J. LOPEZ
-
依托单位:
Prevention of Hip Dysplasia with Thermal Energy
-
批准号:6532925
-
项目类别:
-
资助金额:$10.5万
-
财政年份:2001
-
负责人:MANDI J. LOPEZ
-
依托单位:
Prevention of Hip Dysplasia with Thermal Energy
-
批准号:6871716
-
项目类别:
-
资助金额:$2.3万
-
财政年份:2001
-
负责人:MANDI J. LOPEZ
-
依托单位:
Prevention of Hip Dysplasia with Thermal Energy
-
批准号:6747585
-
项目类别:
-
资助金额:$11.01万
-
财政年份:2001
-
负责人:MANDI J. LOPEZ
-
依托单位:
COXOFEMORAL JOINT MODIFICATION TO PREVENT HIP DYSPLASIA
-
批准号:6055548
-
项目类别:
-
资助金额:$4.33万
-
财政年份:1999
-
负责人:MANDI J. LOPEZ
-
依托单位:
COXOFEMORAL JOINT MODIFICATION TO PREVENT HIP DYSPLASIA
-
批准号:2708413
-
项目类别:
-
资助金额:$3.41万
-
财政年份:1999
-
负责人:MANDI J. LOPEZ
-
依托单位:
海外基金