PULSATILE PEDIATRIC BLOOD PUMP DEVELOPMENT

儿科脉动血泵开发

• 批准号: 2540819
• 负责人: PHILIP LITWAK
• 金额: $ 10万
• 依托单位: ENSION, INC.
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-04-01 至 2001-09-15
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2540819
• 关键词: biomaterial compatibility; biomedical equipment development; circulatory assist; clinical biomedical equipment; heart surgery; hemodynamics; mother /infant health care; pediatrics; sheep; surgery material /equipment

DESCRIPTION (Adapted from applicant's abstract): A widely recognized problem in pediatric cardiac surgery is the lack of suitable mechanical circulatory support devices. In this Phase I program, a consortium consisting of CardioPulmonary Technologies, Inc. (CPT), Nimbus, and the University of Pittsburgh (UOP) plan to utilize rotary pump technology for a blood pump system specifically intended for neonatal/pediatric (N/P) use. This device will be capable of generating pulsatile flow and operating in an uninterrupted fashion for durations consistent with N/P postcardiotomy applications (5-7 days on average). Phase I design activities will focus on the purged fluid seal for the pump, the motor/stator pair, and the features for a closed-loop, pulsatile flow controller. Sufficient pumps and controllers will be fabricated to support in vitro and in vivo testing. The key Phase I demonstration of feasibility of our N/P pump concept will be to successfully perform three in vivo lamb studies for seven-day durations in which the basic hemodynamic performance, biocompatibility and suitability of the pulsatile system for N/P applications is documented. PROPOSED COMMERCIAL APPLICATION: NOT AVAILABLE

描述（改编自申请人摘要）：广泛认可的