DIAGNOSTIC KIT FOR INTERSTITIAL CYSTITIS

间质性膀胱炎诊断套件

• 批准号: 2536598
• 负责人: ADA ELGAVISH
• 金额: $ 10万
• 依托单位: DIACELL, INC.
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-02-15 至 2000-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2536598
• 关键词: cell population study; cell proliferation; cytodiagnosis; diagnosis design /evaluation; diagnostic tests; immunocytochemistry; interstitial cystitis; tissue /cell culture; urinary bladder epithelium; urinary tract disorder diagnosis

DESCRIPTION: (Adapted from the Applicant's Abstract): Interstitial cystitis is a chronic inflammatory disease of the urinary bladder, the pathogenesis of which is unknown. Differentiation between IC and other causes of chronic pelvic pain is difficult, and the diagnosis of IC is one of exclusion. The investigator has developed a series of measurements (e.g., colony size, proliferative rate) on urothelial cells that appear to change in patients with IC. The goal of this phase 1 STTR application is to evaluate the ability of these assays to predict the diagnosis of interstitial cystitis and to develop them into a useful diagnostic test. PROPOSED COMMERCIAL APPLICATION: NOT AVAILABLE

描述：（改编自申请人摘要）：间质性 膀胱炎是膀胱的慢性炎性疾病， 其发病机制尚不清楚。 IC与其他的区别 慢性盆腔疼痛的病因很难，IC的诊断是 一个是排斥。 研究人员开发了一系列 测量（例如，集落大小、增殖率）对尿路上皮细胞的影响 在IC患者中似乎发生了变化。 本阶段的目标1 STTR应用是为了评估这些检测方法预测 间质性膀胱炎的诊断，并发展成为一个有用的 诊断测试 拟议商业应用：不可用

项目成果

A hypothesis for the etiology of interstitial cystitis.

间质性膀胱炎病因学的假设。

• DOI: 10.1007/978-1-4419-8889-8_43
• 发表时间: 2003
• 期刊: Advances in experimental medicine and biology
• 作者: Elgavish,Ada