EXTENSION OF THE NHLBI GROWTH AND HEALTH STUDY

这项赠款申请的总体目标是继续 肥胖与心血管疾病发展的纵向研究 一大群黑白人群(N=2379)的疾病(心血管疾病)危险因素 在9岁和10岁时参加NHLBI生长与健康计划的女孩 在三个中心进行研究(NGHS)，目前正在跟踪调查整个年龄 15-16。在这段时间里，大多数种群已经成熟， 肥胖症的种族差异变得更加明显。然而，种族问题 与成人肥胖相关的心血管危险因素的差异不像 然而，这是显而易见的。 继续进行3年多的纵向调查将遵循 进入青壮年的队列，提供对影响 青春期晚期和成年期早期肥胖和心血管疾病的危险因素 黑人女性和白人女性之间的区别。重要的是要 测量吸烟、缺乏运动和身体状况差等行为 随着女孩进入收养这些高风险的年龄，他们的饮食 行为，并将其与肥胖和其他心血管风险联系起来 各种因素。 对心理社会风险因素的审查也将是 我们预计，肥胖风险的认知等因素， 身体满意度、偏爱的身体形象、节食习惯、文化 喜好、自尊的变化、情绪对饮食的影响 模式和饮食失调风险因素影响肥胖和体重 维修。这些参数中的种族差异将与 肥胖的发展也与社会经济地位有关。

The overall objective of this grant application is to continue the longitudinal investigation of the development of obesity and cardiovascular disease (CVD) risk factors on a large cohort (N=2379) of black and white girls who were enrolled at age 9 and 10 in the NHLBI Growth and Health Study (NGHS) at three centers, and are presently being followed through age 15-16. During this period most of the cohort have reached maturation, and racial differences in obesity have become more pronounced. However, racial differences in CVD risk factors associated with adult obesity were not as yet evident. Continuing the longitudinal investigation for 3 more years will follow the cohort into young adulthood, providing insight on the factors that affect obesity and CVD risk factors in late adolescence and early adulthood, and how they differ between black and white females. It is important to measure behaviors such as cigarette smoking, physical inactivity, and poor diet as the girls enter the age when they are adopting these high-risk behaviors, and relate them to obesity and other cardiovascular risk factors. The examination of psychosocial risk factors will also be an objective of NGHS III. We expect that factors such as perceptions of obesity risks, body satisfaction, preferred body image, dieting practices, cultural preferences, changes in self-esteem, emotional influences on eating patterns, and eating disorder risk factors affect obesity and weight maintenance. Racial differences in these parameters will be associated with obesity development and also be related to socioeconomic status.