COGNITIVE PROCESSES IN PTSD--FOCUS ON DOMESTIC VIOLENCE

创伤后应激障碍（PTSD）的认知过程——关注家庭暴力

• 批准号: 2675463
• 负责人: Patricia A Resick
• 金额: $ 43.95万
• 依托单位: UNIVERSITY OF MISSOURI-ST. LOUIS
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-08-01 至 2000-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2675463
• 关键词: behavior prediction; behavioral /social science research tag; clinical research; cortisol; crime victims; depression; dexamethasone suppression test; dissociative hysteria; female; human subject; model design /development; neuropsychological tests; posttraumatic stress disorder; psychological models; racial /ethnic difference; spouse abuse

The proposed study will extend previous research on information processing theory of LSD by applying an established assessment paradigm to a population of women exposed to repetitive violence by their intimate partners. There are four purposes for this project: 1) To test a model to predict level of trauma pathology among women battered by intimate partners at the time of assessment and four months later; 2) To study dissociation by means of a multimethod assessment to examine whether a differential pattern found with high level dissociators among rape victims is replicated within a sample of battered women; 3) To study physiological reactivity and psychoendocrine alterations in battered women with PTSD, depression, both, or neither disorders; and 4) To examine patterns of reaction and recovery within and across African-American and white samples. The sample of 525 battered women will be drawn from shelter residents and nonresidential battered women's programs. Women will be assessed twice, first between one and two:months after leaving the relationship and then again four months later. The multimodal assessment battery consists of questionnaires, interviews, and a structured laboratory assessment within which psychophysiological responses are measured. Women will be assessed with a battery of self-report inventories on a laptop computer and a clinician administered interview of PTSD (CAPS). Two hundred women will participate in the laboratory portion. The lab will consist of five phases: initial baseline, neutral recall, baseline 2, trauma recall, and final baseline. During these phases, heart rate, skin conductance, and movements will be recorded. A subsample of 150 women will also participate in the dexamethasone challenge. They will have blood drawn at the first assessment session and will return the next morning for a second blood draw after taking dexamethasone that evening. The laboratory and biochemical assessments will be conducted twice, four months apart, to examine recovery.

拟议的研究将扩展先前关于信息的研究 应用既定评估的LSD加工理论 通过以下方式向遭受反复暴力的妇女人口提供范例 他们的亲密伴侣。这个项目有四个目的： 1)测试预测女性创伤病理水平的模型 在评估时被亲密伴侣殴打和四次 几个月后；2)用多种方法研究解离 评估以检查是否存在差异模式 强奸案受害者中的高水平解离者在 受虐妇女样本；3)研究生理反应性和 创伤后应激障碍受虐女性的精神内分泌改变， 抑郁症，两种或两种都不是；以及4)检查模式 非裔美国人内部和整个非洲裔美国人和 白色样本。525名被虐待妇女的样本将从 收容所居民和非住宅区受虐妇女方案。 女性将接受两次评估，第一次是一到两个月： 在离开这段关系之后，四个月后又回来了。 多模式评估组合由问卷组成， 面谈，以及结构化的实验室评估，在 测量心理生理反应。女性将接受评估 笔记本电脑上有一组自我报告的库存， 临床医生对创伤后应激障碍(CAPS)进行访谈。两百 女性将参加实验室部分。实验室将会 由五个阶段组成：初始基线、中性召回、基线 2、创伤回忆和最终基线。在这些阶段，心脏 将记录心率、皮肤电导和运动。小样本 150名女性也将参加地塞米松挑战。 他们将在第一次评估会议上抽血，并将 服用后第二天早上回来进行第二次抽血 当晚地塞米松。实验室和生化 评估将进行两次，间隔四个月，以审查 恢复。