COGNITIVE PROCESSES IN PTSD: TREATMENT

PTSD 的认知过程：治疗

• 批准号: 6739647
• 负责人: Patricia A Resick
• 金额: $ 36.69万
• 依托单位: UNIVERSITY OF MISSOURI-ST. LOUIS
• 依托单位国家: 美国
• 财政年份: 1994
• 资助国家: 美国
• 起止时间: 1994-05-01 至 2006-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6739647
• 关键词: behavioral /social science research tag; clinical research; cognitive behavior therapy; coping; emotions; female; human subject; human therapy evaluation; interview; posttraumatic stress disorder; rape; self concept; women' s health

DESCRIPTION (Adapted from the Applicant's Abstract): This proposal is for a competing renewal of a treatment outcome study on Posttraumatic Stress Disorder (PTSD). The current study is a clinical trial comparing cognitive processing therapy (CPT) with prolonged exposure and a minimal attention waiting-list condition for the treatment of PTSD among victims of rape. The goal of the proposed study is to examine the individual procedural elements of CPT by using a dismantling design. In addition, a secondary goal is to determine if these elements have differential efficacy in the treatment of primary and secondary emotions that are associated with PTSD. Third, the study will examine the generalization of CPT from the treatment of female rape victims to female victims of physical assault. The study will also examine the efficacy of the three methods on self-reported health status. The study will include 120 female participants who are victims of rape or physical assault and are suffering from PTSD. Participants will be randomly assigned to one of the three treatment conditions: cognitive processing therapy, cognitive therapy, or written exposure therapy. Participants in the study will be administered a battery of interviews and self-report measures of symptoms and cognitions. Guilt and shame will be studied as secondary emotions along with a range of beliefs about oneself and the world. In addition, two different types of physiological assessment (verbal processing and startle) will be used to determine if the individual procedural elements of CPT have a differential effect on verbally or situationally accessed memory. Heart rate, skin conductance response, and EMG will be assessed. Participants will be assessed at pretreatment, posttreatment, and at 6-months follow-up. In addition, the participants will be further assessed on a self-report measure of PTSD every week during treatment. The proposed study should make an important contribution to knowledge about treatment and recovery from PTSD. At a theoretical level, the proposed study will also provide an opportunity to investigate theoretical mechanisms hypothesized to be involved in recovery from PTSD.

描述（改编自申请人的摘要）：本提案是针对 创伤后应激障碍治疗结果研究的竞争性更新 （PTSD）。目前的研究是一项临床试验， 长期暴露和最小关注等待列表的CPT治疗 强奸受害者的PTSD治疗条件。的目标 建议的研究是通过使用 一种可拆卸的设计。此外，第二个目标是确定这些 元素在治疗原发性和继发性 与创伤后应激障碍有关的情绪第三，研究将审查 将CPT从女性强奸受害者的治疗推广到女性 身体攻击的受害者。这项研究还将研究 三是自我报告健康状况。该研究将包括120名女性 强奸或人身攻击的受害者， 创伤后应激障碍参与者将被随机分配到三种治疗之一， 条件：认知加工疗法，认知疗法，或书面 暴露疗法研究参与者将接受一系列 访谈和症状和认知的自我报告措施。内疚和羞耻 将作为次要情绪沿着一系列信念来研究， 自己和世界。此外，两种不同类型的生理 评估（言语处理和惊吓）将用于确定 CPT的个别程序要素对口头或 情境访问内存心率、皮肤电导反应和EMG 将被评估。将在治疗前、治疗后、 和6个月随访时。此外，与会者还将进一步 在治疗期间每周进行一次创伤后应激障碍的自我报告评估。的 拟议的研究应作出重要贡献的知识， 治疗和恢复创伤后应激障碍。在理论层面，研究建议 也将提供一个研究理论机制的机会 被认为与创伤后应激障碍的康复有关

项目成果

Participant reactions to a pretreatment research assessment during a treatment outcome study for PTSD.

PTSD 治疗结果研究期间参与者对治疗前研究评估的反应。

• DOI: 10.1002/jts.20428
• 发表时间: 2009
• 期刊: Journal of traumatic stress
• 影响因子: 3.3
• 作者: Resick,PatriciaA;Iverson,KatherineM;Artz,CarolineE
• 通讯作者: Artz,CarolineE

Positive Association Between Nightmares and Heart Rate Response to Loud Tones: Relationship to Parasympathetic Dysfunction in PTSD Nightmares.

噩梦与心率对大声响的反应之间的正相关：与 PTSD 噩梦中副交感功能障碍的关系。

• DOI: 10.1097/nmd.0000000000000641
• 发表时间: 2017
• 期刊: The Journal of nervous and mental disease
• 作者: Tanev,KaloyanS;Orr,ScottP;Pace-Schott,EdwardF;Griffin,Michael;Pitman,RogerK;Resick,PatriciaA
• 通讯作者: Resick,PatriciaA

Does Cognitive-Behavioral Therapy for PTSD Improve Perceived Health and Sleep Impairment?

• DOI: 10.1002/jts.20418
• 发表时间: 2009-06-01
• 期刊: JOURNAL OF TRAUMATIC STRESS
• 影响因子: 3.3
• 作者: Galovski, Tara E.;Monson, Candice;Resick, Patricia A.
• 通讯作者: Resick, Patricia A.

Treatment of posttraumatic stress disorder reduces suicidal ideation.

• DOI: 10.1002/da.22117
• 发表时间: 2013-10
• 期刊: DEPRESSION AND ANXIETY
• 影响因子: 7.4
• 作者: Gradus, Jaimie L.;Suvak, Michael K.;Wisco, Blair E.;Marx, Brian P.;Resick, Patricia A.
• 通讯作者: Resick, Patricia A.

Cognitive Processing Therapy for Substance-Involved Sexual Assault: Does an Account Help or Hinder Recovery?

• DOI: 10.1002/jts.22674
• 发表时间: 2021-08
• 期刊: Journal of traumatic stress
• 影响因子: 3.3
• 作者: Jaffe AE;Kaysen D;Smith BN;Galovski T;Resick PA
• 通讯作者: Resick PA