PROSPECTIVE EVALUATION OF IMPLANT SUPPORTED BRIDGES

描述：本申请建议继续研究多年 6-10。研究人员正在研究刚性和非刚性的影响 将天然牙齿附着到骨整合种植体上。上一个 申请建议招募 50 名缺失所有患者的患者 上颌牙齿和下颌右、左第二前磨牙 用于研究的臼齿。每位患者接受一次两阶段治疗 下颌骨两侧均涂有羟基磷灰石种植体 第一磨牙区。第一下颌骨上附着有一个桥 前磨牙和羟基磷灰石种植体。桥的一侧是 使用刚性技术将其固定在前磨牙和种植体上 在另一侧，桥是用非刚性的半刚性材料固定的 精密槽附件。上颌假牙与牙桥相对。 患者每 6 个月接受一次检查。标准化放射线照片， 每六次进行一次软组织检查和满意度评估 几个月。 研究人员计划在每个研究项目中招募 20 名患者。 前两年和第三年有 10 名患者。然而，他们的 招聘过程花费的时间比计划的要长。共有 42 个 患者是在研究的前 4 年招募的。大部分 患者是在第 3 年和第 4 年而不是在第 3 年和第 4 年被招募和恢复的 在第一年和第二年。研究人员没有改变研究 来自先前批准的拨款的协议。他们正在要求 资金用于支持 42 名患者再进行 5 年的随访。他们 不打算招募任何新患者。 骨整合种植体之间桥接的影响 天然牙齿将通过牙龈测量进行评估 出血、牙菌斑和牙石指数、附着牙龈的存在， 使用标准射线照片以及牙齿和种植体的垂直骨质流失 流动性。

DESCRIPTION: This application proposes continuing a study for years 6-10. The investigators are studying the effect of rigid and non-rigid attachment of natural teeth to osseointegrated implants. The previous applications recommended recruiting fifty patients who were missing all the maxillary teeth and mandibular right and left second premolars and molars for the study. Each patient received a one two-staged hydroxyapatite-coated implant on each side of the mandible in the first molar area. A bridge was attached to the first mandibular premolar and the hydroxyapatite implant. On one side, the bridge was attached to the premolar and implant using a rigid technique while on the opposite side, the bridge was attached using a non-rigid, semi- precision slot attachment. A maxillary denture opposed the bridges. The patients are examined every 6 months. Standardized radiographs, soft tissue exams, and satisfaction evaluations are performed every six months. The investigators had planned to recruit 20 patients in each of the first 2 years and 10 patients in the third year. However, their recruitment process has taken longer than planned. A total of 42 patients was recruited during the first 4 years of the study. Most of the patients were recruited and restored in years 3 and 4 rather than in years 1 and 2. The investigators have not changed the study protocol from the previously approved grant. They are requesting funding to support 5 more years of follow-up on the 42 patients. They do not plan to recruit any new patients. The effects of the bridge attachment between osseointegrated implants and natural teeth will be evaluated using measurements of gingival bleeding, plaque and calculus indices, presence of attached gingiva, vertical bone loss using standard radiographs, and tooth and implant mobility.