PROSPECTIVE EVALUATION OF IMPLANT SUPPORTED BRIDGES

描述：本申请建议继续研究数年 6胜10负。研究人员正在研究刚性和非刚性的影响。 天然牙与骨结合植入物的连接。上一次 申请推荐招募50名错过所有 上颌牙齿和下颌左右第二前磨牙和 这项研究的磨牙。每个患者都接受了一次两次的 下颌两侧羟基磷灰石涂层种植体的临床应用 第一磨牙区域。一座桥连接在第一个下颌骨上 前磨牙和羟基磷灰石种植体。在一边，桥是 使用坚固的技术连接到前磨牙和种植体 对面，该桥是用非刚性、半刚性连接的 精密槽附件。一颗上颌假牙与桥相对。 患者每6个月检查一次。标准化的射线照片， 软组织检查和满意度评估每六次进行一次 月份。 调查人员原计划在每个医院招募20名患者。 前2年10例，第3年10例。然而，他们的 招聘过程花费的时间比计划的要长。总共42个 患者是在研究的前4年招募的。大部分 这些患者是在第三年和第四年招募和恢复的，而不是 在第一年和第二年。研究人员没有改变研究 从先前批准的拨款中提取的协议。他们要求 资金支持对42名患者再进行5年的随访。他们 不打算招募任何新患者。 骨结合种植体间桥接的效果观察 而天然牙齿将通过牙龈测量进行评估 出血，菌斑和结石指数，附着性牙龈， 使用标准X线片以及牙齿和种植体的垂直骨丢失 机动性。

DESCRIPTION: This application proposes continuing a study for years 6-10. The investigators are studying the effect of rigid and non-rigid attachment of natural teeth to osseointegrated implants. The previous applications recommended recruiting fifty patients who were missing all the maxillary teeth and mandibular right and left second premolars and molars for the study. Each patient received a one two-staged hydroxyapatite-coated implant on each side of the mandible in the first molar area. A bridge was attached to the first mandibular premolar and the hydroxyapatite implant. On one side, the bridge was attached to the premolar and implant using a rigid technique while on the opposite side, the bridge was attached using a non-rigid, semi- precision slot attachment. A maxillary denture opposed the bridges. The patients are examined every 6 months. Standardized radiographs, soft tissue exams, and satisfaction evaluations are performed every six months. The investigators had planned to recruit 20 patients in each of the first 2 years and 10 patients in the third year. However, their recruitment process has taken longer than planned. A total of 42 patients was recruited during the first 4 years of the study. Most of the patients were recruited and restored in years 3 and 4 rather than in years 1 and 2. The investigators have not changed the study protocol from the previously approved grant. They are requesting funding to support 5 more years of follow-up on the 42 patients. They do not plan to recruit any new patients. The effects of the bridge attachment between osseointegrated implants and natural teeth will be evaluated using measurements of gingival bleeding, plaque and calculus indices, presence of attached gingiva, vertical bone loss using standard radiographs, and tooth and implant mobility.