FHS--MOLECULAR GENETICS & GENETIC EPIDEMIOLOGY

FHS--分子遗传学

• 批准号: 2750554
• 负责人: Gerardo Heiss
• 金额: $ 22.54万
• 依托单位: UNIV OF NORTH CAROLINA CHAPEL HILL
• 依托单位国家: 美国
• 财政年份: 1996
• 资助国家: 美国
• 起止时间: 1996-08-15 至 2000-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2750554
• 关键词: African American; atherosclerosis; cardiovascular disorder epidemiology; clinical research; cooperative study; coronary disorder; disease /disorder proneness /risk; family genetics; gene environment interaction; genetic mapping; human genetic material tag; human population genetics; human subject

DESCRIPTION (Adapted from the applicants' abstract) FHS: Molecular Genetics and Genetic Epidemiology is submitted collaboratively by seven research groups including four clinical sites (University of North Carolina; Boston University; University of Minnesota; and University of Utah), a molecular biology laboratory (University of Utah), a coordinating center (Washington University, St. Louis, MO), a chemistry laboratory (University of Minnesota). The proposed study will perform state-of-the-art molecular genetic and genetic epidemiology studies using the extensive data on family and medical histories, risk factors, life style, blood specimens and banked DNA, previously collected by the Family Heart Study (FHS). The purpose is to identify and characterize genes of coronary heart disease (CHD) and atherosclerosis, familial environmental factors and behavioral characteristics, and to advance our understanding of how they interact with one another in the development of clinical outcomes.

描述（改编自申请人摘要）FHS：分子遗传学