STRUCTURE OF NEW RETROVIRAL AGENT: PLANT EXTRACT: INTEGRASE

新型逆转录病毒剂的结构：植物提取物：Integrase

• 批准号: 6123259
• 负责人: Myun Ki Han
• 金额: --
• 依托单位: BOSTON UNIVERSITY MEDICAL CAMPUS
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-07-01 至 1999-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6123259
• 关键词: Invertebrata; biomaterials; biomedical resource; carbohydrates; immunology; inflammation; lymphatic system; spectrometry; structural biology

A component or mixture of component has been obtained from a plant source. The apparently small molecule(s), whose N1W is below 1000 Da, showed anti-integrase activity andmay have potential as a retroviral agent. The material has UV absorptivity and is highly fluorescent; these properties are being utilized to guide purification. MALDI-TOF MS is being used to characterize samples purified on thin layer chromatographic plates.

从工厂获得一种成分或一种成分的混合物 消息来源。表面看来很小的分子(S)，其N1W低于1000Da， 显示出抗整合酶活性，可能是一种潜在的逆转录病毒 探员。该材料具有紫外线吸收能力，具有很强的荧光； 这些性质被用来指导提纯。MALDI-TOF MS用于表征在薄层上提纯的样品 色谱板。