MASTERS PROGRAM IN PATIENT-ORIENTED RESEARCH

该申请要求为为期两年的以患者为导向的研究教学硕士项目提供资金，该项目由哥伦比亚大学内科医生和外科医生学院（P 和 S）以及公共卫生学院 (SPH) 联合开发。 该项目将由医学教授、GCRC 项目主任兼哥伦比亚欧文临床研究中心主任 Henry Ginsberg 和副教授兼生物统计学临床研究方法硕士学位课程主任 Melissa Begg 领导。 该提案的目标是制定一个强大的、多学科的教学培训计划，为年轻的研究人员作为临床科学家的独立职业做好准备。 具体目标是：（1）开发以患者为导向的研究课程，获得公共卫生学院硕士学位，这将为年轻研究人员开始临床研究职业生涯提供广泛的基础。 (2) 组建一个由活跃的临床研究科学家组成的咨询委员会，该委员会将制定并应用指南，以选择和评估年轻研究者作为硕士课程的学位候选人。 (3) 启动并维持长期的跟踪计划，以确定硕士课程对职业发展的影响。 顾问委员会由 P and S、SPH、牙科和口腔外科学院以及护理学院的高级临床研究人员组成。 课程将以生物统计学和流行病学为中心，但也包括药理学、实验室方法、负责任的研究行为和资助机会等必修课程。 将举办一系列持续的研究座谈会，其中包括有关药物开发、FDA 要求和专利问题的研讨会。 所有学位候选人都将撰写一份美国国立卫生研究院风格的资助金，该资助金将由生物统计部门的一名成员赞助，并由全校各院系和学校的高级研究人员指导。 哥伦比亚大学及其主要附属机构圣卢克斯·罗斯福医院中心和哈莱姆医院中心的博士后研究员、讲师和助理教授的潜在申请者群体庞大且才华横溢，许多 NIH 资助的培训补助金和 K 奖已经到位。 申请者中女性和少数族裔的比例很高。 公共卫生学院、内科医生和外科医生学院以及长老会医院对拟议项目做出了杰出的承诺，承诺每年为 12 名学生提供全额学费奖学金：这将确保每年都有优秀的申请者群体。

This application requests funding for a two-year, didactic Master's Program in Patient-Oriented Research that is being developed jointly by the College of Physicians and Surgeons (P and S) and the School of Public Health (SPH) of Columbia University. The program will be led by Henry Ginsberg, Professor of Medicine, Program Director of the GCRC, and Director of the Irving Center for Clinical Research at Columbia, and Melissa Begg, Associate Professor and Director of the Master's degree track in Clinical Research Methods in Biostatistics. The goal of this proposal is to develop a strong, multidisciplinary didactic training program that will prepare young investigators for independent careers as clinical scientists. The Specific Aims are: (1)To develop a curriculum in Patient-Oriented Research, leading to a Master's degree from the School of Public Health, that will provide a broad foundation for young investigators beginning their careers in clinical investigation. (2) To assemble an Advisory Board of active clinical research scientists that will establish and apply guidelines for the selection and evaluation of young investigators as degree candidates in the Master's program. (3) To initiate and maintain a long-term follow-up program to determine the impact of the Master's program on career development. An Advisory Board has been drawn from senior clinical investigators at P and S, SPH, the School of Dental and Oral Surgery, and the School of Nursing. The curriculum will be centered upon biostatistics and epidemiology, but will include required courses in pharmacology, laboratory methods, the responsible conduct of research and funding opportunities. There will be a continuing series of research colloquia which will include seminars on drug development, FDA requirements and patent issues. All degree candidates will write an NIH-style grant that will be sponsored by a member of the Division of Biostatistics and mentored by senior investigators from departments and schools Campus-wide. The potential applicant pool of postdoctoral fellows, Instructors, and Assistant Professors at Columbia and its major affiliates, the St. Lukes Roosevelt Hospital Center and the Harlem Hospital Center, is large and talented, with many NIH-funded training grants and K awards already in place. Women and minorities are very well represented in the applicant pool. The School of Public Health, the College of Physicians and Surgeons, and the Presbyterian Hospital have made an outstanding commitment to the proposed program by pledging to support twelve students each year with full tuition scholarships: this will ensure an outstanding applicant pool each year.