NRSA Training Core

NRSA 培训核心

• 批准号: 9511938
• 负责人: HENRY N GINSBERG
• 金额: $ 114.22万
• 依托单位: COLUMBIA UNIVERSITY HEALTH SCIENCES
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-07-01 至 2021-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9511938
• 关键词: Address; Adverse effects; Biomedical Research; Client satisfaction; Competence; Data Science; Discipline; Education; Effectiveness; Faculty; Genetic; Goals; Health; Healthcare; Human Resources; Institutes; Learning; Mentors; Methods; Molecular; Monitor; National Research Service Awards; Output; Patient Rights; Patients; Phenotype; Postdoctoral Fellow; Precision Medicine Initiative; Program Development; Research; Research Infrastructure; Research Personnel; Resources; Risk; Science; Students; TNFSF15 gene; Time; Training; Translating; United States National Institutes of Health; Universities; biomarker development; career; career development; clinical practice; cost; experience; faculty research; genomic data; human disease; implementation science; improved; improved outcome; innovation; member; novel; pre-doctoral; precision medicine; programs; skills

TL1 Precision Medicine Program Abstract Our goal is to establish the TRANSFORM TL1 Precision Medicine (PM) Program to provide training and mentoring in the methods and applications of PM to pre-docs, post-docs, junior faculty, and a wide range of research personnel. PM is the right treatment for the right patient at the right time; it offers the opportunity to increase effectiveness of health care at reduced cost with improved outcomes, decreased adverse effects, and greater patient satisfaction. Through a suite of innovative programs, we will enhance career development, translational capabilities, and collaborative skills of faculty and research team members from diverse disciplines around the theme of PM. Our goals are to: (i) develop innovative education and career development programs, building on and extending our many successful existing programs, that will build competency in our scholars and trainees to engage in interdisciplinary teamwork, make new discoveries, and translate those discoveries to clinical practice/patient benefit; (ii) demonstrate the effectiveness of those programs through continuous monitoring and assessment for quality improvement, using key metrics to evaluate the impact of our educational programs on research output, career trajectories, and continued engagement in biomedical research; and (iii) To disseminate findings on novel educational delivery approaches, new methods for assessing student learning, and best practices in enhancing interdisciplinary team science skills to our partners at Columbia, the members of the CTSA consortium, and educational programs throughout the nation. Columbia University is a significant contributor, nationally and world-wide, to research in genetics, genomics, data science, phenotyping and risk prediction, biomarker development, and the molecular basis of human disease; as well as to interdisciplinary team science training. These strengths will allow us to offer new and enhanced coursework in PM; create pre-doc and post-doc programs to increase competency in PM; develop short-term training that allows pre-docs to gain facility with PM strategies and methods; and evaluate our educational efforts in an ongoing way to improve programming. In 2013, Columbia's President, Lee Bollinger, announced the University-wide PM Initiative aimed at bringing together all units within Columbia to address the full spectrum of research, education, and implementation sciences in this field. Thus, this is the ideal time to undertake these goals. We are confident we can achieve these goals because of the outstanding CUMC research portfolio, the momentum provided by the new, University-wide PM initiative, our 10+ years of experience in administering successful training and mentoring programs, and the personnel and infrastructure provided by our Irving Institute resources. Through all these means, we are poised to contribute substantially to NIH's goal of building a larger and exceptionally well-prepared biomedical research workforce prepared to advance health through the potential of PM.

TL1精密医学计划摘要 我们的目标是建立转型TL1 Precision Medicine（PM）计划，以提供培训和 在PM到术前的方法和应用中进行指导 研究人员。 PM是适当的患者的正确治疗方法；它提供了机会 通过改善结果，减少不良影响和 更高的患者满意度。通过一系列创新计划，我们将增强职业发展， 翻译能力以及来自多样化的教师和研究团队成员的协作技能 围绕PM主题的学科。我们的目标是：（i）发展创新的教育和职业 开发计划，建立并扩展了我们许多成功的现有计划，这些计划将建立 我们的学者和学员的能力有能力从事跨学科团队合作，做出新的发现和 将这些发现转化为临床实践/患者利益； （ii）证明那些人的有效性 通过持续监控和评估质量改进的程序，使用关键指标 评估我们的教育计划对研究成果，职业轨迹和继续的影响 参与生物医学研究； （iii）传播有关新型教育的发现 方法，评估学生学习的新方法以及增强跨学科的最佳实践 我们在哥伦比亚的合作伙伴，CTSA财团的成员和教育的团队科学技能 全国各地的计划。哥伦比亚大学是全国和全球的重要贡献者， 遗传学，基因组学，数据科学，表型和风险预测，生物标志物发展和 人类疾病的分子基础；以及跨学科团队科学培训。这些优势 将使我们能够在PM中提供新的和增强的课程工作；创建大型和大型课程计划以增加 PM的能力；开发短期培训，使培训可以通过PM策略获得设施，并 方法;并以持续改进编程的方式评估我们的教育工作。 2013年， 哥伦比亚总裁李·布林格（Lee Bollinger）宣布了旨在将所有人汇集在一起​​的大学范围内PM倡议 哥伦比亚境内的单位应对其中的全部研究，教育和实施科学 场地。因此，这是实现这些目标的理想时间。我们有信心我们可以实现这些目标 由于出色的COMC研究组合，新的大学范围内PM提供的势头 主动性，我们在管理成功培训和指导计划方面拥有10年以上的经验， 我们的欧文研究所资源提供的人员和基础设施。通过所有这些手段，我们是 准备为NIH的目标做出基本贡献，即建立更大且精心准备的生物医学 研究人员准备通过PM的潜力来提高健康。