NRSA Training Core

NRSA 培训核心

• 批准号: 9511938
• 负责人: HENRY N GINSBERG
• 金额: $ 114.22万
• 依托单位: COLUMBIA UNIVERSITY HEALTH SCIENCES
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-07-01 至 2021-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9511938
• 关键词: Address; Adverse effects; Biomedical Research; Client satisfaction; Competence; Data Science; Discipline; Education; Effectiveness; Faculty; Genetic; Goals; Health; Healthcare; Human Resources; Institutes; Learning; Mentors; Methods; Molecular; Monitor; National Research Service Awards; Output; Patient Rights; Patients; Phenotype; Postdoctoral Fellow; Precision Medicine Initiative; Program Development; Research; Research Infrastructure; Research Personnel; Resources; Risk; Science; Students; TNFSF15 gene; Time; Training; Translating; United States National Institutes of Health; Universities; biomarker development; career; career development; clinical practice; cost; experience; faculty research; genomic data; human disease; implementation science; improved; improved outcome; innovation; member; novel; pre-doctoral; precision medicine; programs; skills

TL1 Precision Medicine Program Abstract Our goal is to establish the TRANSFORM TL1 Precision Medicine (PM) Program to provide training and mentoring in the methods and applications of PM to pre-docs, post-docs, junior faculty, and a wide range of research personnel. PM is the right treatment for the right patient at the right time; it offers the opportunity to increase effectiveness of health care at reduced cost with improved outcomes, decreased adverse effects, and greater patient satisfaction. Through a suite of innovative programs, we will enhance career development, translational capabilities, and collaborative skills of faculty and research team members from diverse disciplines around the theme of PM. Our goals are to: (i) develop innovative education and career development programs, building on and extending our many successful existing programs, that will build competency in our scholars and trainees to engage in interdisciplinary teamwork, make new discoveries, and translate those discoveries to clinical practice/patient benefit; (ii) demonstrate the effectiveness of those programs through continuous monitoring and assessment for quality improvement, using key metrics to evaluate the impact of our educational programs on research output, career trajectories, and continued engagement in biomedical research; and (iii) To disseminate findings on novel educational delivery approaches, new methods for assessing student learning, and best practices in enhancing interdisciplinary team science skills to our partners at Columbia, the members of the CTSA consortium, and educational programs throughout the nation. Columbia University is a significant contributor, nationally and world-wide, to research in genetics, genomics, data science, phenotyping and risk prediction, biomarker development, and the molecular basis of human disease; as well as to interdisciplinary team science training. These strengths will allow us to offer new and enhanced coursework in PM; create pre-doc and post-doc programs to increase competency in PM; develop short-term training that allows pre-docs to gain facility with PM strategies and methods; and evaluate our educational efforts in an ongoing way to improve programming. In 2013, Columbia's President, Lee Bollinger, announced the University-wide PM Initiative aimed at bringing together all units within Columbia to address the full spectrum of research, education, and implementation sciences in this field. Thus, this is the ideal time to undertake these goals. We are confident we can achieve these goals because of the outstanding CUMC research portfolio, the momentum provided by the new, University-wide PM initiative, our 10+ years of experience in administering successful training and mentoring programs, and the personnel and infrastructure provided by our Irving Institute resources. Through all these means, we are poised to contribute substantially to NIH's goal of building a larger and exceptionally well-prepared biomedical research workforce prepared to advance health through the potential of PM.

TL1精准医学计划摘要 我们的目标是建立转型TL1精准医学(PM)计划，以提供培训和 对博士后、博士后、初级教员和广泛领域的PM方法和应用进行指导 研究人员。PM是在正确的时间对正确的患者进行正确的治疗；它提供了 以更低的成本提高卫生保健的有效性，改善结果，减少不良影响，以及 更大的患者满意度。通过一系列创新计划，我们将促进职业发展， 来自不同地区的教职员工和研究团队成员的翻译能力和协作技能 围绕PM主题的纪律我们的目标是：(一)发展创新教育和事业 开发计划，在我们许多成功的现有计划的基础上建立和扩展，这将建立 我们的学者和学员有能力参与跨学科的团队合作，做出新的发现，以及 将这些发现转化为临床实践/患者利益；(Ii)展示这些发现的有效性 通过持续监控和评估质量改进的计划，使用关键指标来 评估我们的教育项目对研究成果、职业发展轨迹的影响，并继续 参与生物医学研究；及(Iii)传播有关创新教育的研究结果 方法、评估学生学习的新方法以及加强跨学科的最佳实践 为我们在哥伦比亚的合作伙伴、CTSA联盟的成员和教育部门提供团队科学技能 全国各地的节目。哥伦比亚大学是全国和世界范围内的重要贡献者 遗传学、基因组学、数据科学、表型和风险预测、生物标记物开发以及 人类疾病的分子基础；以及跨学科团队科学培训。这些优势 将允许我们在PM中提供新的和增强的课程；创建博士前和博士后课程以增加 具备项目管理能力；开展短期培训，使预科医生能够熟练掌握项目管理战略和 方法；并以持续不断的方式评估我们的教育努力，以改进方案编制。2013年， 哥伦比亚大学校长Lee Bollinger宣布了大学范围内的PM倡议，旨在将所有 哥伦比亚大学内部的单位在这方面处理研究、教育和实施科学的全范围 菲尔德。因此，现在是实现这些目标的理想时机。我们有信心实现这些目标 由于杰出的CUMC研究组合，新的大学范围内的PM提供的动力 计划，我们在管理成功的培训和指导计划方面的10多年经验，以及 人员和基础设施由我们欧文研究所提供的资源。通过所有这些手段，我们正在 准备为NIH的目标做出重大贡献，即建立一个规模更大、准备特别完善的生物医学 研究人员准备通过PM的潜力来促进健康