TESTING OF A NEW SYSTEM FOR CIRCULATORY SUPPORT

测试新的循环支持系统

• 批准号: 2644909
• 负责人: THOMAS C ROBINSON
• 金额: $ 40.4万
• 依托单位: MISSION MEDICAL, INC.
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-04-10 至 2000-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2644909
• 关键词: animal tissue; biomaterial compatibility; biomedical automation; biomedical equipment development; blood circulation; blood flow measurement; circulatory assist; clinical biomedical equipment; computer program /software; evaluation /testing; extracorporeal circulation; hemolysis; human tissue

DESCRIPTION (Adapted from applicant's abstract): The long-term objectives of this research are the development and widespread use of an automated, safer, and more effective pumping system for patient circulatory support. The benefits in health care include: substantially lower blood damage; reduced thrombus accumulation; longer pump life; inherent and accurate blood flow rate control; elimination of backflow; limited, safe blood pressure levels; and lower costs compared to centrifugal blood pumping systems. This system also provided significant control an safety advantages compared to peristaltic pumps. The specific aims of this proposed research are functional optimizations, further improvements in blood compatibility, and development and fabrication of a complete practical system. A technologically innovative pumping control algorithm will be refined and optimized to maximize flow accuracy and speed of response and increase the flow control range for blood pumps covering the entire pediatric and adult ranges of operation. This system will be extensively tested in vitro with bovine blood and subsequently with human blood. PROPOSED COMMERCIAL APPLICATION: Not available.

描述（改编自申请人摘要）：长期