Genetic regulation of wing reduction in the emu

鸸鹋翅膀减少的遗传调控

• 批准号: DP190100890
• 负责人: A/Prof Craig Smith
• 金额: $ 27.11万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2019
• 资助国家: 澳大利亚
• 起止时间: 2019-03-02 至 2022-03-01
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP190100890
• 关键词: Genetic; regulation; wing; reduction; emu

This project aims to examine the genetic mechanisms that generate limb diversity, using wing reduction in the emu as a model. A hot topic in biology at present is evolutionary developmental biology, or how genes control morphological diversity. This project will explore the functions of two novel genes implicated in wing reduction. The project expects to expand knowledge in the area of developmental biology, and limb morphogenesis specifically. It will bear upon the phylogeny of flightlessness among birds. It also has potential implications for studying human limb deformities. Overall, the project will enhance our understanding of how genes control the great diversity that we see in nature.

该项目旨在使用emu的机翼减少作为模型来检查产生肢体多样性的遗传机制。目前，生物学的热门话题是进化发展生物学，或基因如何控制形态学多样性。该项目将探索与翼还原有关的两个新基因的功能。该项目预计将扩大发育生物学领域的知识，并特别是肢体形态发生。它将承受鸟类无飞行的系统发育。它还对研究人肢畸形有潜在的影响。总体而言，该项目将增强我们对基因如何控制我们在自然界中看到的巨大多样性的理解。