Chicken and ChIPs; genetic control of avian gonadal development

鸡肉和薯条;

• 批准号: DP160103881
• 负责人: A/Prof Craig Smith
• 金额: $ 25.57万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2016
• 资助国家: 澳大利亚
• 起止时间: 2016-02-29 至 2018-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP160103881
• 关键词: Chicken; ChIPs; genetic; control; avian

This project aims to improve our understanding of gonad formation at the genetic level, using unique approaches that exploit the chicken embryo as a model system. Gonad formation during embryonic life provides an excellent model for studying the genetic control of development. The project plans to use innovative methods to study novel and known gonad-determining genes. The project seeks to make a substantial contribution to our understanding of cell fate decisions, sex determination and gonad development. It also potentially has application to the poultry industry by illuminating those genes and pathways that can be targeted to modulate sex determination in chickens, which is a goal of the industry.

这个项目旨在通过利用鸡胚胎作为模型系统的独特方法，在遗传水平上提高我们对性腺形成的理解。胚胎时期性腺的形成为研究发育的遗传控制提供了一个很好的模型。该项目计划使用创新的方法来研究新的和已知的性腺决定基因。该项目旨在为我们理解细胞命运决定、性别决定和性腺发育做出实质性贡献。它还有可能应用于家禽业，通过阐明那些可以有针对性地调节鸡的性别决定的基因和途径，这是该行业的一个目标。