CORE--ANIMAL FACILITY

产品描述：（申请人描述）动物设施为研究所使用的所有研究动物提供护理，并确保其符合伦理使用。 物种包括小鼠（转基因、基因敲除、突变、无胸腺裸Scid和纯品系）、大鼠、兔和非洲爪蟾。动物机构工作人员按照主要研究者的指示对动物进行几乎所有程序，特别是那些常规程序。 动物设施技术人员能够执行血液样本采集、注射、肿瘤接种、灌注、卵母细胞手术回收、管饲、尾部活检和耳切等程序。 该设施保存研究所所有转基因小鼠品系的谱系。 这种集中式系统使研究者不必雇用和培训技术人员来执行这些常规程序和管理任务，从而提供了非常高效的服务。 自1988年以来，该机构已获得美国实验动物管理认证协会（AAALAC）的认证。

Description: (Applicant's Description) The Animal Facility provides care for, and ensures the ethical use of, all research animals used at the Institute. Species include mice (transgenic, gene knockout, mutant, athymic nude Scid, and axenic strains), rats, rabbits, and Xenopus laevis. The Animal Facility staff conducts almost all procedures on animals, especially those that are routine in nature, following instructions of the principal investigator. Animal Facility technicians are able to perform procedures such as blood sample collection, injections, tumor inoculation, perfusions, surgical recovery of oocytes, gavaging, tail biopsies, and ear notching. The Facility maintains the pedigrees for all lines of transgenic mice held at the Institute. This centralized system frees the Investigator from having to hire and train technicians to perform these routine procedure and husbandry tasks, and results in a service that is very efficient. This facility has been accredited by the American Association for Accreditation of Laboratory Animal Care (AAALAC) since 1988.