CORE--CLINICAL

核心--临床

• 批准号: 6201468
• 负责人: J. Dennis Fortenberry
• 金额: $ 13.85万
• 依托单位: INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-09-01 至 2000-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6201468
• 关键词: adolescence (12-20); biomedical facility; biopsy; blood chemistry; data collection; female; human subject; interview; personal log /diary; questionnaires; sexually transmitted diseases; tissue resource /registry; urinalysis

The purpose of the Clinical Core is to provide biological specimens and behavioral data to all of the individual research projects. This core will be located in Indianapolis. Core research personnel will enroll and maintain the cohort of middle adolescent female research subjects over the five year duration of the center, collect all required biological samples (genitourinary swabs, endocervical secretions, vaginal lavages, urine, cervical biopsies, and blood), behavioral information (self-administered questionnaires and personal interviews), and provide interim reproductive health examinations and data collection to facilitate subject retention. Research personnel will include research coordinator, research nurse practitioner, and two Disease Intervention Specialists (DIS) from the Marion Country Health Department. The research nurse will obtain all biological specimens. DIS will perform two important fieldwork functions: (1) contact sexual partners of subjects to obtained personal information, urine samples, provide appropriate antibiotic treatment when partners of infected women prefer to be treated outside of the Marion County STD Clinic (Bell Flower); (2) weekly contact with all subjects during the three month period of intense data collection to obtain urine samples and self-directed vaginal swabs, personal behavioral diaries and interview information.

临床中心的目的是提供生物标本和