DEVELOPING AND IMPROVING INSTITUTIONAL ANIMAL RESOURCES

开发和改善机构动物资源

• 批准号: 3059226
• 负责人: THOMAS B CLARKSON
• 金额: $ 6.15万
• 依托单位: WAKE FOREST UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1991
• 资助国家: 美国
• 起止时间: 1991-08-20 至 1992-08-19
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3059226
• 关键词: animal colony; building /facility design /renovation

This is an application to develop and improve the animal resource of the Comparative Medicine Clinical Research Center (CMCRC) of the Bowman Gray School of Medicine. Specifically, the application is to improve nonhuman primate obstetric, prenatal and neonatal care at the CMCRC. The expected outcome is to improve the reproductive health and performance of three breeding colonies of macaques (Macaca mulatta, M. fascicularis, M. arctoides) used in biomedical research and training. There are three additions to current programs proposed: 1) a high risk obstetric/prenatal ward for housing pregnant monkeys at high risk for poor pregnancy outcome; 2) a neonatal intensive care unit for orphans, newborns delivered by cesarean section, and infants rejected by their mothers; and 3) a nursery equipped to allow care, socialization, and surveillance of infants not requiring intensive care but-still requiring special care. These improvements will result in better survival of colony-born monkeys, thus supporting primate conservation. Additionally, the improvements sought will provide a source for training post-DVM fellows in nonhuman primate obstetrics, prenatal medicine and neonatology. Finally, the resource enhancements will facilitate development of a program in developmental psychobiology, with a particular focus on diseases of human relevance.

这是一个应用程序，以开发和改善的动物资源， 鲍曼格雷比较医学临床研究中心（CMCRC） 医学院的。 具体而言，该应用程序是为了改善非人类 灵长类产科、产前和新生儿护理中心。 预期 结果是改善三个国家的生殖健康和业绩， 猕猴（Macaca mulatta，M.束状孢M. arctoides）用于生物医学研究和培训。 有三 对现有方案提出的补充：1）高风险产科/产前 用于饲养妊娠结局差的高风险妊娠猴的病房; 2)新生儿重症监护室，为孤儿，新生儿交付 剖腹产，婴儿拒绝他们的母亲;和3）托儿所 配备设备，允许照顾，社会化，并监测婴儿不 需要重症监护，但仍然需要特别护理。 这些 这些改进将使出生在殖民地的猴子生存得更好， 支持灵长类动物保护 此外，所寻求的改进 将为非人灵长类动物DVM后研究员的培训提供来源 产科、产前医学和生殖医学。 最后，资源 增强将促进发展中国家的计划的发展， 心理生物学，特别关注与人类相关的疾病。