CLINICAL BIOMECHANICS OF THE CERVICAL SPINE

颈椎的临床生物力学

• 批准号: 3155778
• 负责人: MANOHAR M PANJABI
• 金额: $ 16.93万
• 依托单位: YALE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1982
• 资助国家: 美国
• 起止时间: 1982-02-01 至 1988-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3155778
• 关键词: X ray; biomechanics; body movement; computed axial tomography; human tissue; laminectomy; ligaments; nervous system disorder diagnosis; neural degeneration; spinal cord injury; spine; vertebrae; videotape /videodisc

Cervical spine injuries, degenertion (spondylosis), nerve root compression (radiculopathy) and spinal cord compression (myelopathy) are the major causes of pain, deformity and neurological disfunction in the cervical region. Studies of the spinal column alone, while important, provide limited information about the cord and nerve roots. The purpose of the present proposal is to study in a comprehensive manner the mechanical basis of local, radicular and myelopathic symptomatology in the cervical spine. Such information is not available presently. This comprehensive study has three basic parts. Firstly, to determine ligamentous strains and intervertebral foramenal changes due to physiological movements of the cervical spine. Secondly, to measure physiological movements of, and strains in,, the nerve roots and spinal cord. Finally, to quantify 3-dimensional anatomy of the cervical spine in various physiological postures using cryomicrotome sectioning, X-rays and CT-scans. Significance of this work will be in several different areas. The comprehensive set of biomechanical data about the functioning relationships between the various components of the cervical spine system, namely, vertebrae, ligaments, spinal cord and nerve roots will be available for the first time. It will provide the basis for understanding the functioning of the cervical spine system. Thereby making it possible to correlate precisely the anatomic derangements with clinical presentation of symptoms in a patient. It will also be helpful in the design of new and more efficient diagonostic and treatment modalities for the various problems of the cervical spine.

颈椎损伤、退行性变（颈椎病）、神经根受压 （神经根病）和脊髓压迫（脊髓病）是主要的 颈椎疼痛、畸形和神经功能障碍的原因 地区 对脊柱的研究虽然很重要， 关于脊髓和神经根的信息有限。 的目的 目前的建议是全面研究机械基础， 颈椎的局部、神经根和脊髓病变。 目前没有这方面的资料。 这项综合研究有三个基本部分。 第一，确定 由于韧带拉伤和椎间孔变化 颈椎的生理运动。 第二，衡量 神经根和脊髓的生理运动和应变 线. 最后，为了量化颈椎的三维解剖结构， 使用冷冻切片机切片，X射线和 CT扫描 这项工作的意义将在几个不同的领域。 的 关于功能关系的一套全面的生物力学数据 颈椎系统的各个组成部分之间，即， 脊椎，韧带，脊髓和神经根将可用于 首次 它将为理解 颈椎系统。 从而有可能将 正是解剖学紊乱与临床症状的表现 在病人身上。 它也将有助于设计新的和更多的 有效的诊断和治疗方式的各种问题， 颈椎