Coding of olfactory information in the piriform cortex

梨状皮层嗅觉信息的编码

• 批准号: DP180101034
• 负责人: Prof John Bekkers
• 金额: $ 51.3万
• 依托单位: The Australian National University
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2018
• 资助国家: 澳大利亚
• 起止时间: 2018-09-01 至 2024-07-01
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP180101034
• 关键词: Coding; olfactory; information; piriform; cortex

This project aims to understand how electrical activity in the primary olfactory (piriform) cortex enables mice to recognise and remember odours. By using optical recording techniques together with genetic tools, the project expects to generate new knowledge about how the mammalian brain builds internal representations of the external world. Specific outcomes of the project include new insights into the functional architecture of the piriform cortex and fresh understanding of how olfactory information is encoded and stored in neural circuits. More broadly, the project aims to advance our understanding of how the brain works, with benefits for future improvements in artificial intelligence and brain-machine interfaces.

该项目旨在了解初级嗅觉（梨状）皮层的电活动如何使小鼠识别和记住气味。通过使用光学记录技术和遗传工具，该项目期望产生关于哺乳动物大脑如何构建外部世界的内部表征的新知识。该项目的具体成果包括对梨状皮层功能结构的新见解，以及对嗅觉信息如何在神经回路中编码和存储的新理解。更广泛地说，该项目旨在增进我们对大脑如何工作的理解，有利于人工智能和脑机接口的未来改进。