Excitability and hyperexcitability of neural circuits in the rodent piriform cortex

啮齿动物梨状皮层神经回路的兴奋性和超兴奋性

• 批准号: nhmrc : 585462
• 负责人: Prof John Bekkers
• 金额: $ 24.79万
• 依托单位: Australian National University
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2010
• 资助国家: 澳大利亚
• 起止时间: 2010-01-01 至 2014-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/excitability-hyperexcitability-neural-piriform-cortex/81463
• 关键词: Excitability; hyperexcitability; neural; circuits; rodent

We are studying the properties of neurons (nerve cells) and brain circuits that enable mammals to recognise and remember odours. Our experiments will focus on neurons in the odour-processing region of the cerebral cortex of mice. This work will answer fundamental questions about how the brain interprets sensory inputs in order to build a coherent picture of the external world. Our findings will also provide a deeper understanding of the causes of epilepsy, leading to improved treatments.

我们正在研究使哺乳动物能够识别和记忆气味的神经元（神经细胞）和脑回路的特性。我们的实验将集中在老鼠大脑皮层气味处理区域的神经元上。这项工作将回答有关大脑如何解释感官输入以建立对外部世界的连贯图像的基本问题。我们的发现也将提供对癫痫病因的更深入了解，从而改善治疗方法。